Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 3/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10033111 | 0.86 | HTR2C (0.35) | TP53HTR2CTDP1 | |
| SCHEMBL10033138 | 0.85 | SIGMAR1 (0.42) | SIGMAR1HTR2CPOLBRAB9ASMN1; SMN2 | |
| SCHEMBL1709440 | 0.84 | KDM4E (0.32) | — | |
| SCHEMBL10032983 | 0.84 | KDM4E (0.32) | — | |
| SCHEMBL10033181 | 0.81 | KDM4E (0.33) | HTR2C | |
| SCHEMBL1709436 | 0.81 | KDM4E (0.33) | HTR2C | |
| SCHEMBL10032974 | 0.80 | SIGMAR1 (0.44) | SIGMAR1HTR2C | |
| SCHEMBL6917782 | 0.79 | SIGMAR1 (0.45) | SIGMAR1POLBRAB9ASMN1; SMN2 | |
| SCHEMBL1709418 | 0.79 | BCHE (0.32) | HTR2C | |
| SCHEMBL10033139 | 0.78 | SIGMAR1 (0.39) | SIGMAR1HTR2CPOLBRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012046771-A1 | CYCLOALKANE COMPOUND | アステラス製薬株式会社 (JP) | 2012-04-12 | — | — | WO | disclosed |