Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 2/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 5/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 2/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | MC4R | P32245 | 1/20 | 0.30 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10032973 | 0.86 | SIGMAR1 (0.38) | HTR2CTP53TDP1 | |
| SCHEMBL10033089 | 0.80 | HTR2A (0.40) | HTR2COPRL1HTR2AHTR2BGAA | |
| SCHEMBL1709418 | 0.78 | BCHE (0.32) | HTR2CHTR2AHTR2B | |
| SCHEMBL10033105 | 0.76 | TDP1 (0.36) | ALDH1A1TDP1 | |
| SCHEMBL10032986 | 0.74 | KDM1A (0.34) | HTR2CHTR2BGAA | |
| SCHEMBL1709440 | 0.73 | KDM4E (0.32) | ALDH1A1 | |
| SCHEMBL10032983 | 0.73 | KDM4E (0.32) | ALDH1A1 | |
| SCHEMBL1709421 | 0.72 | L3MBTL1 (0.38) | TP53GAAALDH1A1TDP1 | |
| SCHEMBL10032840 | 0.72 | L3MBTL1 (0.37) | GAAALDH1A1TDP1 | |
| SCHEMBL10033179 | 0.72 | ALDH1A1 (0.40) | ALDH1A1TDP1BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012046771-A1 | CYCLOALKANE COMPOUND | アステラス製薬株式会社 (JP) | 2012-04-12 | — | — | WO | disclosed |