Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WNT3A | P56704 | 7/20 | 0.45 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.44 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.44 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.41 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | KMO | O15229 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | DHODH | Q02127 | 2/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.38 |
| ▸ | PLK1 | P53350 | 1/20 | 0.38 |
| ▸ | FLT1 | P17948 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9057614 | 0.88 | BAZ2B (0.53) | WNT3ABAZ2BCYP11B1CYP11B2PTPN2 | |
| SCHEMBL10033150 | 0.78 | FYN (0.51) | BAZ2BPTPN2PTPN1MAP4K4 | |
| SCHEMBL12957239 | 0.78 | HSD17B1 (0.67) | HSD17B1HSD17B2CYP11B1CYP11B2KMO | |
| SCHEMBL24272977 | 0.78 | TSHR (0.56) | PTPN1KMOTDP1FLT1TSHR | |
| SCHEMBL2480995 | 0.77 | CYP3A4 (0.56) | HSD17B1HSD17B2CYP11B1CYP11B2KMO | |
| SCHEMBL13910991 | 0.76 | HSD17B1 (0.63) | HSD17B1HSD17B2CYP11B1CYP11B2KMO | |
| SCHEMBL22530855 | 0.76 | CYP11B1 (0.50) | WNT3ABAZ2BCYP11B1CYP11B2PTPN2 | |
| SCHEMBL27687343 | 0.76 | CYP3A4 (0.54) | HSD17B1HSD17B2CYP11B1CYP11B2KMO | |
| SCHEMBL11991176 | 0.76 | HSD17B1 (0.59) | HSD17B1HSD17B2KMO | |
| SCHEMBL3152503 | 0.75 | CCR1 (0.46) | BAZ2BPTPN2PTPN1CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012014994-A1 | NAPHTHALENE DERIVATIVE | ダイトーケミックス株式会社 (JP) | 2012-02-02 | — | — | WO | disclosed |