SCHEMBL2480995

SCHEMBL2480995

Cc1ccc(-c2cccc(-c3ccccc3)c2)nc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.56
CYP2A6 P11509 1/20 0.56
CCR1 P32246 1/20 0.54
CCR5 P51681 1/20 0.54
CCR8 P51685 1/20 0.54
HDAC6 Q9UBN7 1/20 0.54
HSD17B1 P14061 2/20 0.47
HSD17B2 P37059 2/20 0.47
CYP11B1 P15538 2/20 0.45
CYP11B2 P19099 2/20 0.45
KDM1A O60341 1/20 0.44
KMO O15229 2/20 0.42
MET P08581 1/20 0.42
COMT P21964 1/20 0.42
FLT3 P36888 1/20 0.42
KDR P35968 1/20 0.42
LDHA P00338 1/20 0.41
METAP2 P50579 1/20 0.41
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27687343 0.98 CYP3A4 (0.54) CYP3A4CYP2A6CCR1CCR5CCR8
SCHEMBL503090 0.92 CYP3A4 (0.63) CYP3A4CYP2A6CCR1CCR5CCR8
SCHEMBL17426494 0.87 CYP3A4 (0.54) CYP3A4CYP2A6CCR1CCR5CCR8
SCHEMBL12359222 0.86 CYP3A4 (0.61) CYP3A4CYP2A6CCR1CCR5CCR8
SCHEMBL18267900 0.86 CYP3A4 (0.50) CYP3A4CYP2A6CCR1CCR5CCR8
SCHEMBL2480932 0.86 CYP3A4 (0.50) CYP3A4CYP2A6CCR1CCR5CCR8
SCHEMBL404433 0.86 CYP3A4 (0.66) CYP3A4CYP2A6CCR1CCR5CCR8
SCHEMBL21022948 0.86 CYP2A6 (0.57) CYP3A4CYP2A6CCR1CCR5CCR8
SCHEMBL18174581 0.85 CYP3A4 (0.43) CYP3A4CYP2A6CCR1CCR5CCR8
SCHEMBL3771686 0.85 CYP3A4 (0.49) CYP3A4CYP2A6CCR1CCR5CCR8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12022727-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2024-06-25 US disclosed
US-20240025934-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-01-25 US disclosed
US-11753427-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-09-12 US disclosed
US-11753425-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-09-12 US disclosed
US-20230276696-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORP (US) 2023-08-31 US disclosed
US-11616203-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-03-28 US disclosed
US-11584719-B2 Organic electroluminescent compound and organic electroluminescent device comprising the same ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. 2023-02-21 US disclosed
US-11239434-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2022-02-01 US disclosed
US-11228004-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2022-01-18 US disclosed
EP-3551623-B1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ROHM & HAAS ELECT MATERIALS KOREA LTD (KR) 2021-09-22 EP disclosed
US-7709100-B2 Electroluminescent efficiency UNIVERSAL DISPLAY CORPORATION (US) 2010-05-04 US disclosed
US-7709100-B2 Electroluminescent efficiency UNIVERSAL DISPLAY CORPORATION (US) 2010-05-04 US disclosed
US-7709100-B2 Electroluminescent efficiency UNIVERSAL DISPLAY CORPORATION (US) 2010-05-04 US disclosed
EP-1763902-A2 STABLE AND EFFICIENT ELECTROLUMINESCENT MATERIALS Universal Display Corporation (US) 2007-03-21 EP disclosed
US-20070003789-A1 Stable and efficient electroluminescent materials UNIVERSAL DISPLAY CORPORAITON 2007-01-04 US disclosed
US-20070003789-A1 Stable and efficient electroluminescent materials UNIVERSAL DISPLAY CORPORAITON 2007-01-04 US disclosed
US-20070003789-A1 Stable and efficient electroluminescent materials UNIVERSAL DISPLAY CORPORAITON 2007-01-04 US disclosed
WO-2006014599-A2 STABLE AND EFFICIENT ELECTROLUMINESCENT MATERIALS UNIVERSAL DISPLAY CORPORATION (US) 2006-02-09 WO disclosed
US-20060008671-A1 Electroluminescent efficiency UNIVERSAL DISPLAY CORPORATION 2006-01-12 US disclosed
US-20060008673-A1 Electroluminescent efficiency THE UNIVERSITY OF SOUTHERN CALIFORNIA 2006-01-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11616203-B2 Organic electroluminescent materials and devices ICOSLG, APOL1, OXA1L CYP3A4 1950/4885CYP2A6 3619/4885CCR1 920/4885
US-20240025934-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES SSB, RO60, LIFR CYP3A4 3160/4885CYP2A6 3466/4885CCR1 314/4885
US-11239434-B2 Organic electroluminescent materials and devices L1CAM, LEF1, EPCAM CYP3A4 784/4885CYP2A6 2210/4885CCR1 1570/4885
US-20060008671-A1 Electroluminescent efficiency EML4, LEF1, ESR1 CYP3A4 418/4885CYP2A6 1729/4885CCR1 3253/4885
US-11584719-B2 Organic electroluminescent compound and organic electroluminescent device comprising the same ELAVL1, SOD1, TELO2 CYP3A4 2369/4885CYP2A6 4423/4885CCR1 4763/4885
US-11228004-B2 Organic electroluminescent materials and devices OCIAD2, OCIAD1, ICOSLG CYP3A4 739/4885CYP2A6 2304/4885CCR1 873/4885
US-20060008673-A1 Electroluminescent efficiency EML4, LEF1, ESR1 CYP3A4 418/4885CYP2A6 1729/4885CCR1 3253/4885
US-12022727-B2 Organic electroluminescent materials and devices OCIAD1, OSBP, OCIAD2 CYP3A4 1418/4885CYP2A6 2038/4885CCR1 2519/4885
US-11753427-B2 Organic electroluminescent materials and devices OCIAD1, OSBP, OCIAD2 CYP3A4 1640/4885CYP2A6 2193/4885CCR1 2661/4885
US-11753425-B2 Organic electroluminescent materials and devices SSB, RO60, LIFR CYP3A4 3160/4885CYP2A6 3466/4885CCR1 314/4885
US-20230276696-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, PORCN CYP3A4 1960/4885CYP2A6 4389/4885CCR1 2709/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.