Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 11/20 | 0.51 |
| ▸ | MAP4K4 | O95819 | 3/20 | 0.49 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.49 |
| ▸ | KDR | P35968 | 2/20 | 0.49 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.49 |
| ▸ | CDK8 | P49336 | 2/20 | 0.49 |
| ▸ | ACVR1 | Q04771 | 2/20 | 0.49 |
| ▸ | MST1R | Q04912 | 2/20 | 0.49 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.49 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.49 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.49 |
| ▸ | CSNK1G2 | P78368 | 2/20 | 0.49 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.49 |
| ▸ | MAP4K5 | Q9Y4K4 | 2/20 | 0.49 |
| ▸ | PLK4 | O00444 | 1/20 | 0.49 |
| ▸ | DCLK1 | O15075 | 1/20 | 0.49 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.49 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.49 |
| ▸ | PAK4 | O96013 | 1/20 | 0.49 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22801096 | 0.82 | FYN (0.58) | FYNMAP4K4CLK4KDRMAPK8 | |
| SCHEMBL5991753 | 0.80 | FYN (0.55) | FYNMAP4K4CLK4KDRMAPK8 | |
| SCHEMBL14988455 | 0.79 | FYN (0.56) | FYNMAP4K4CLK4KDRMAPK8 | |
| SCHEMBL2560542 | 0.79 | LDHA (0.68) | FYNMAP4K4CLK4KDRMAPK8 | |
| SCHEMBL10033044 | 0.78 | WNT3A (0.45) | MAP4K4PTPN2PTPN1BAZ2B | |
| SCHEMBL9057614 | 0.76 | BAZ2B (0.53) | PTPN2PTPN1BAZ2B | |
| SCHEMBL22801095 | 0.75 | FYN (0.53) | FYNMAP4K4CLK4KDRMAPK8 | |
| SCHEMBL30937997 | 0.74 | MAP4K4 (0.55) | FYNMAP4K4CLK4KDRMAPK8 | |
| SCHEMBL17742695 | 0.74 | MAP4K4 (0.55) | FYNMAP4K4CLK4KDRMAPK8 | |
| SCHEMBL7768635 | 0.73 | ALDH1A1 (0.66) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012014994-A1 | NAPHTHALENE DERIVATIVE | ダイトーケミックス株式会社 (JP) | 2012-02-02 | — | — | WO | disclosed |