SCHEMBL10033087

SCHEMBL10033087

C=C(C[C@@H]1CC[C@@H](N)[C@H](C2CCCCC2)C1)OCC

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1709495 0.68 MEN1 (0.38) NPSR1
SCHEMBL10033086 0.67 KDM1A (0.40) TSHR
SCHEMBL20664064 0.62 THRB (0.44)
SCHEMBL20934549 0.62 THRB (0.44)
SCHEMBL25263661 0.62 THRB (0.44)
SCHEMBL25919102 0.62 LIPA (0.36)
SCHEMBL29117712 0.61 ALDH1A1 (0.35) TSHRNPSR1
SCHEMBL10455924 0.61 KMT2A (0.39)
Hydrochloric Acid SCHEMBL25302442 0.61 THRB (0.42)
Hydrochloric Acid SCHEMBL25302443 0.61 THRB (0.42)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012046771-A1 CYCLOALKANE COMPOUND アステラス製薬株式会社 (JP) 2012-04-12 WO disclosed