Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1709367 | 0.85 | MEN1 (0.46) | MEN1KMT2AABCC1DPP4HPGD | |
| SCHEMBL10033085 | 0.79 | HTR2A (0.40) | DPP4HTR2AHTR2CHTR2B | |
| SCHEMBL6917416 | 0.78 | MDM2 (0.48) | TP53MDM2 | |
| SCHEMBL10033086 | 0.77 | KDM1A (0.40) | MEN1KMT2ASMN1; SMN2TP53HTR2C | |
| SCHEMBL10033089 | 0.74 | HTR2A (0.40) | DPP4HTR2AHTR2CHTR2B | |
| SCHEMBL1709360 | 0.74 | L3MBTL1 (0.43) | MEN1KMT2AHPGDSMN1; SMN2TP53 | |
| SCHEMBL1709472 | 0.71 | DGAT1 (0.39) | SMN1; SMN2 | |
| SCHEMBL1709371 | 0.68 | MEN1 (0.43) | MEN1KMT2AABCC1HPGDSMN1; SMN2 | |
| SCHEMBL10033087 | 0.68 | TSHR (0.30) | NPSR1 | |
| SCHEMBL1709417 | 0.67 | DPP4 (0.42) | MEN1KMT2ADPP4HPGDHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012046771-A1 | CYCLOALKANE COMPOUND | アステラス製薬株式会社 (JP) | 2012-04-12 | — | — | WO | disclosed |