Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AB1 | P08238 | 5/20 | 0.41 |
| ▸ | DHODH | Q02127 | 3/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | LYN | P07948 | 1/20 | 0.35 |
| ▸ | BTK | Q06187 | 1/20 | 0.35 |
| ▸ | EIF2AK3 | Q9NZJ5 | 1/20 | 0.34 |
| ▸ | TDO2 | P48775 | 1/20 | 0.34 |
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14988263 | 0.79 | HSP90AB1 (0.40) | HSP90AB1DHODHGRIN1GRIN2BSIGMAR1 | |
| SCHEMBL10032806 | 0.77 | DHODH (0.43) | HSP90AB1DHODHGRIN1GRIN2BABL1 | |
| SCHEMBL14988205 | 0.73 | MEN1 (0.45) | — | |
| SCHEMBL21021276 | 0.71 | LMNA (0.37) | HSP90AB1GRIN1GRIN2BLYNBTK | |
| SCHEMBL10094719 | 0.71 | TRPV1 (0.46) | HSP90AB1TDO2GRM5 | |
| SCHEMBL26739761 | 0.71 | DHODH (0.53) | DHODH | |
| SCHEMBL14007418 | 0.71 | KDM4E (0.33) | LYNBTKCRHR1 | |
| SCHEMBL20049814 | 0.71 | GRIN2B (0.44) | GRIN1GRIN2BABL1EIF2AK3GRM5 | |
| SCHEMBL12319845 | 0.70 | SIGMAR1 (0.40) | HSP90AB1SIGMAR1GRM5 | |
| SCHEMBL14039912 | 0.70 | PDE3B (0.44) | HSP90AB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012014994-A1 | NAPHTHALENE DERIVATIVE | ダイトーケミックス株式会社 (JP) | 2012-02-02 | — | — | WO | disclosed |