Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | LYN | P07948 | 2/20 | 0.37 |
| ▸ | BTK | Q06187 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | AGPAT2 | O15120 | 1/20 | 0.36 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.36 |
| ▸ | FABP4 | P15090 | 1/20 | 0.36 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.36 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 3/20 | 0.35 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10304908 | 0.82 | LMNA (0.46) | LMNAAGPAT2HSP90AB1NISCHPDE3B | |
| SCHEMBL21021589 | 0.80 | APP (0.45) | LYNBTKCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL15317985 | 0.78 | KDM4E (0.44) | LMNACYP3A4HPGDAPPALDH1A1 | |
| SCHEMBL14039912 | 0.78 | PDE3B (0.44) | LMNAHSP90AB1NISCHPDE3BPDE3A | |
| SCHEMBL10032806 | 0.75 | DHODH (0.43) | LYNBTKCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL30377758 | 0.73 | NISCH (0.52) | LMNAAGPAT2NISCH | |
| SCHEMBL9139591 | 0.73 | NISCH (0.52) | LMNAAGPAT2NISCH | |
| SCHEMBL13652436 | 0.73 | ACHE (0.42) | LMNAHPGDNISCHMAPTALDH1A1 | |
| SCHEMBL16348086 | 0.73 | ABL1 (0.51) | CYP1A2NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL3756908 | 0.72 | S1PR1 (0.46) | CYP1A2CYP3A4CYP2D6HPGDCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3283459-B1 | MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2019-05-22 | — | — | EP | disclosed |