SCHEMBL10033186 — predicted protein targets

Predicted protein targets (top 14)

	gene	UniProt	supporting neighbours	confidence
▸	TEAD1	P28347	2/20	0.39

▸	RECQL	P46063	1/20	0.37

▸	GAA	P10253	1/20	0.36

▸	L3MBTL1	Q9Y468	1/20	0.36

▸	CACNA1A	O00555	1/20	0.36

▸	CACNA2D1	P54289	1/20	0.36

▸	CACNB1	Q02641	1/20	0.36

▸	MTTP	P55157	2/20	0.35

▸	SMO	Q99835	1/20	0.35

▸	CASR	P41180	2/20	0.35

▸	TRPM8	Q7Z2W7	1/20	0.35

▸	TACR1	P25103	3/20	0.35

▸	MDM2	Q00987	2/20	0.35

▸	MEN1	O00255	1/20	0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL10033189	0.77	TACR1 (0.39)	TEAD1RECQLMTTPSMOTACR1
SCHEMBL10033110	0.77	MAPK1 (0.43)	GAATACR1
SCHEMBL10033124	0.71	HSD11B1 (0.39)	RECQLGAATACR1
SCHEMBL10032829	0.69	FFAR1 (0.41)	RECQLGAAL3MBTL1TACR1
SCHEMBL5474484	0.67	GAA (0.67)	RECQLGAAL3MBTL1CASRMEN1
SCHEMBL5474480	0.67	GAA (0.67)	RECQLGAAL3MBTL1CASRMEN1
SCHEMBL2104997	0.67	GAA (0.58)	RECQLGAAL3MBTL1CASRMEN1
SCHEMBL2104996	0.67	GAA (0.58)	RECQLGAAL3MBTL1CASRMEN1
SCHEMBL10032830	0.66	GRIA4 (0.41)	RECQLGAAL3MBTL1MEN1
SCHEMBL8706897	0.66	TACR1 (0.52)	TACR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2012046771-A1	CYCLOALKANE COMPOUND	アステラス製薬株式会社 (JP)	2012-04-12	—	—	WO	disclosed