Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 2/20 | 0.41 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.37 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.37 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.37 |
| ▸ | ACACB | O00763 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TACR1 | P25103 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | UBE2M | P61081 | 1/20 | 0.34 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.34 |
| ▸ | POLQ | O75417 | 1/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | RORC | P51449 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10032830 | 0.90 | GRIA4 (0.41) | GAARECQLHCRTR2USP2ALOX15 | |
| SCHEMBL10033178 | 0.80 | L3MBTL1 (0.39) | ALDH1A1SMN1; SMN2RECQLL3MBTL1 | |
| SCHEMBL10033189 | 0.79 | TACR1 (0.39) | FFAR1ALDH1A1TACR1RECQL | |
| SCHEMBL10032824 | 0.77 | GRIA4 (0.40) | RECQLHCRTR2 | |
| SCHEMBL10033135 | 0.75 | KCNN4 (0.38) | FFAR1TAS1R3TAS1R1TAS1R2ALDH1A1 | |
| SCHEMBL10033182 | 0.73 | BRD4 (0.38) | GAAALDH1A1SMN1; SMN2RECQLL3MBTL1 | |
| SCHEMBL10033184 | 0.72 | L3MBTL1 (0.35) | TAS1R3TAS1R1TAS1R2ACACBGAA | |
| SCHEMBL10033188 | 0.71 | MTOR (0.36) | GAAALDH1A1SMN1; SMN2TACR1RECQL | |
| SCHEMBL10033180 | 0.71 | SLC6A2 (0.34) | L3MBTL1 | |
| SCHEMBL10033177 | 0.70 | GRIA4 (0.38) | TAS1R3TAS1R1TAS1R2HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012046771-A1 | CYCLOALKANE COMPOUND | アステラス製薬株式会社 (JP) | 2012-04-12 | — | — | WO | disclosed |