Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 5/20 | 0.39 |
| ▸ | TEAD1 | P28347 | 2/20 | 0.37 |
| ▸ | CCR5 | P51681 | 1/20 | 0.36 |
| ▸ | MTTP | P55157 | 1/20 | 0.35 |
| ▸ | SMO | Q99835 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | MDM2 | Q00987 | 3/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10033178 | 0.85 | L3MBTL1 (0.39) | RECQLALDH1A1TSHR | |
| SCHEMBL10032824 | 0.84 | GRIA4 (0.40) | CCR5RECQL | |
| SCHEMBL10033185 | 0.83 | RECQL (0.33) | RECQLKDM4EALDH1A1TSHR | |
| SCHEMBL10033182 | 0.82 | BRD4 (0.38) | RECQLKDM4EALDH1A1TSHR | |
| SCHEMBL1709396 | 0.80 | ALDH1A1 (0.38) | TACR1KDM4EALDH1A1 | |
| SCHEMBL10033188 | 0.79 | MTOR (0.36) | TACR1RECQLALDH1A1TSHR | |
| SCHEMBL10032829 | 0.79 | FFAR1 (0.41) | TACR1RECQLFFAR1ALDH1A1 | |
| SCHEMBL10033186 | 0.77 | TEAD1 (0.39) | TACR1TEAD1MTTPSMORECQL | |
| SCHEMBL10033130 | 0.77 | TACR1 (0.41) | TACR1KDM4EALDH1A1 | |
| SCHEMBL10032830 | 0.77 | GRIA4 (0.41) | RECQLKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012046771-A1 | CYCLOALKANE COMPOUND | アステラス製薬株式会社 (JP) | 2012-04-12 | — | — | WO | disclosed |