Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 2/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13701491 | 1.00 | ALDH1A1 (0.54) | ALDH1A1TSHRKMT2AMEN1CYP1A2 | |
| SCHEMBL3092338 | 0.89 | CYP2A6 (0.42) | ALDH1A1APPTDP1CYP2A6CA1 | |
| SCHEMBL3079657 | 0.89 | CYP2A6 (0.42) | ALDH1A1APPTDP1CYP2A6CA1 | |
| SCHEMBL452831 | 0.89 | ALDH1A1 (0.68) | ALDH1A1TSHRKMT2AMEN1CYP1A2 | |
| SCHEMBL469946 | 0.89 | TSHR (0.55) | ALDH1A1TSHRAPPACHETDP1 | |
| SCHEMBL470004 | 0.83 | TSHR (0.48) | ALDH1A1TSHRCYP2C19APPACHE | |
| SCHEMBL4754769 | 0.83 | TSHR (0.48) | ALDH1A1TSHRCYP2C19APPACHE | |
| SCHEMBL24871316 | 0.81 | ALDH1A1 (0.56) | ALDH1A1TSHRKMT2AMEN1CYP1A2 | |
| SCHEMBL23661307 | 0.81 | TSHR (0.46) | ALDH1A1TSHRKMT2AMEN1CYP3A4 | |
| SCHEMBL16509905 | 0.81 | ALDH1A1 (0.56) | ALDH1A1TSHRKMT2AMEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012032211-A1 | DENDRITIC STRUCTURES BASED ON TETRAARYLMETHANE | UNIVERSIDADE DE SANTIAGO DE COMPOSTELA (ES) | 2012-03-15 | — | — | WO | disclosed |
| US-20090227812-A1 | TETRAPHENYLMETHANE SKELETON-CONTAINING COMPOUND | FUJIFILM CORPORATION (JP) | 2009-09-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090227812-A1 | TETRAPHENYLMETHANE SKELETON-CONTAINING COMPOUND | PAH, TSNAX, ZFX | ALDH1A1 4467/4885TSHR 2120/4885KMT2A 1393/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.