Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 3/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA5A | P35218 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4754769 | 1.00 | TSHR (0.48) | TSHRACHETDP1KIF11APP | |
| SCHEMBL469946 | 0.93 | TSHR (0.55) | TSHRACHETDP1KIF11APP | |
| SCHEMBL2703573 | 0.88 | KIF11 (0.37) | KIF11APPCYP2C9 | |
| SCHEMBL17469595 | 0.85 | ACHE (0.50) | TSHRACHETDP1KIF11CYP2D6 | |
| SCHEMBL19004134 | 0.85 | ACHE (0.50) | TSHRACHETDP1KIF11CYP2D6 | |
| SCHEMBL4392845 | 0.85 | ACHE (0.50) | TSHRACHETDP1KIF11CYP2D6 | |
| SCHEMBL23661307 | 0.84 | TSHR (0.46) | TSHRACHETDP1KIF11HPGD | |
| SCHEMBL13149752 | 0.83 | ACHE (0.54) | TSHRACHEAPPHPGDALOX15 | |
| SCHEMBL10033199 | 0.83 | ALDH1A1 (0.54) | TSHRACHETDP1APPCYP2C19 | |
| SCHEMBL13701491 | 0.83 | ALDH1A1 (0.54) | TSHRACHETDP1APPCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012032211-A1 | DENDRITIC STRUCTURES BASED ON TETRAARYLMETHANE | UNIVERSIDADE DE SANTIAGO DE COMPOSTELA (ES) | 2012-03-15 | — | — | WO | disclosed |