Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | ACHE | P22303 | 4/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | CA5A | P35218 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.32 |
| ▸ | MLYCD | O95822 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | KIF11 | P52732 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4754769 | 0.93 | TSHR (0.48) | TSHRACHETDP1APPNPC1 | |
| SCHEMBL470004 | 0.93 | TSHR (0.48) | TSHRACHETDP1APPNPC1 | |
| SCHEMBL23661307 | 0.91 | TSHR (0.46) | TSHRACHETDP1ALDH1A1KIF11 | |
| SCHEMBL13701491 | 0.89 | ALDH1A1 (0.54) | TSHRACHETDP1APPNPC1 | |
| SCHEMBL10033199 | 0.89 | ALDH1A1 (0.54) | TSHRACHETDP1APPNPC1 | |
| SCHEMBL13149752 | 0.89 | ACHE (0.54) | TSHRACHEAPPMAPTALDH1A1 | |
| SCHEMBL13149758 | 0.89 | ACHE (0.54) | TSHRACHETDP1APPNPC1 | |
| SCHEMBL11878908 | 0.86 | TSHR (0.71) | TSHRACHETDP1NPC1MAPT | |
| SCHEMBL28553350 | 0.86 | APP (0.40) | TSHRAPPCA1CA2HDAC8 | |
| SCHEMBL1986810 | 0.86 | APP (0.40) | TSHRAPPCA1CA2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012032211-A1 | DENDRITIC STRUCTURES BASED ON TETRAARYLMETHANE | UNIVERSIDADE DE SANTIAGO DE COMPOSTELA (ES) | 2012-03-15 | — | — | WO | disclosed |