Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | AHR | P35869 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.36 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.36 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.36 |
| ▸ | ITGAL | P20701 | 1/20 | 0.36 |
| ▸ | CRHBP | P24387 | 2/20 | 0.32 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29973180 | 1.00 | ALOX5 (0.38) | ALOX5AHRLMNAHTTABCG2 | |
| SCHEMBL6994886 | 0.81 | ALOX5 (0.38) | ALOX5AHRLMNAHTTABCG2 | |
| SCHEMBL8764608 | 0.77 | ALOX5 (0.35) | ALOX5AHRLMNAHTTABCG2 | |
| SCHEMBL6990050 | 0.77 | ALOX5 (0.35) | ALOX5AHRLMNAHTTABCG2 | |
| SCHEMBL30185992 | 0.73 | ALOX5 (0.41) | ALOX5AHRLMNAHTTABCG2 | |
| SCHEMBL9289415 | 0.73 | ALOX5 (0.41) | ALOX5AHRLMNAHTTABCG2 | |
| SCHEMBL8976354 | 0.71 | HTR2C (0.33) | AHR | |
| SCHEMBL7267859 | 0.71 | MAP3K14 (0.34) | AHRALDH1A1TSHR | |
| SCHEMBL8976179 | 0.71 | AHR (0.32) | AHR | |
| SCHEMBL6442271 | 0.71 | LMNA (0.32) | ALOX5AHRLMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 103 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210363127-A1 | PROCESS FOR THE PREPARATION OF 2,2-DIFLUORO-1,3-BENZODIOXOLE AND INTERMEDIATES THEREOF | SRF LIMITED (IN) | 2021-11-25 | — | — | US | claimed |
| EP-3860985-A1 | PROCESS FOR THE PREPARATION OF 2,2-DIFLUORO-1,3-BENZODIOXOLE AND INTERMEDIATES THEREOF | SRF LIMITED (IN) | 2021-08-11 | — | — | EP | claimed |
| CN-107936006-B | Synthetic method of rivaroxaban | 浙江美诺华药物化学有限公司 | 2020-06-19 | — | — | CN | claimed |
| WO-2020070759-A1 | PROCESS FOR THE PREPARATION OF 2,2-DIFLUORO-1,3-BENZODIOXOLE AND INTERMEDIATES THEREOF | SRF LIMITED (IN) | 2020-04-09 | — | — | WO | claimed |
| EP-0546418-B1 | Process for the preparation of 5-substituted 2-chloropyridines | BAYER AG (DE) | 2001-10-17 | — | — | EP | claimed |
| EP-0590459-B1 | Process for the preparation of difluoro - and chlorofluorobenzodioxolanes | BAYER AG (DE) | 1997-07-23 | — | — | EP | claimed |
| EP-0423009-B1 | Process for the preparation of 2,2-difluoro-1,3-benzodioxole | RHONE POULENC CHIMIE (FR) | 1995-12-27 | — | — | EP | claimed |
| US-5432290-A | Fluorination | RHONE-POULENC CHIMIE (FR) | 1995-07-11 | — | — | US | claimed |
| US-5350865-A | Fluorination of dichlorobenzodioxole with hydrogen fluoride | BAYER AKTIENGESELLSCHAFT (DE) | 1994-09-27 | — | — | US | claimed |
| EP-0590459-A2 | Process for the preparation of difluoro - and chlorofluorobenzodioxolanes | BAYER AG (DE) | 1994-04-06 | — | — | EP | claimed |
| US-4855367-A | Orthocarbonates | GIBA-GEIGY CORPORATION (US) | 1989-08-08 | — | — | US | claimed |
| EP-0295209-A2 | Esters of orthocarbonic acid | CIBA-GEIGY AG (CH) | 1988-12-14 | — | — | EP | claimed |
| EP-0090769-B1 | PROCESS FOR THE PREPARATION OF 1,2,5,6-TETRAHYDRO-4H-PYRROLO(3,2,1-IJ)-QUINOLIN-4-ONE AND 5-HALO-1,2,3-(1,2,DIHYDROPYRROLO)-4-QUINOLONE INTERMEDIATES | CIBA-GEIGY AG (CH) | 1986-08-20 | — | — | EP | claimed |
| US-4550165-A | FUNGICIDES | CIBA GEIGY CORPORATION (US) | 1985-10-29 | — | — | US | claimed |
| EP-0090769-A2 | Process for the preparation of 1,2,5,6-tetrahydro-4H-pyrrolo(3,2,1-ij)-quinolin-4-one and 5-halo-1,2,3-(1,2,dihydropyrrolo)-4-quinolone intermediates | CIBA-GEIGY AG (CH) | 1983-10-05 | — | — | EP | claimed |
| EP-0004895-B1 | DICHLOROBENZODIOXOLE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS SYNERGETIC AGENTS IN INSECTICIDAL AND ACARICIDAL COMPOSITIONS | BAYER AG (DE) | 1981-04-01 | — | — | EP | claimed |
| JP-6211832-A | — | — | None | — | — | JP | disclosed |
| JP-3184972-A | — | — | None | — | — | JP | disclosed |
| EP-0006978-A2 | Benzyl esters with fluorinated ether and/or thioether groups, their preparations and their use as insecticides; intermediate products and their preparations | BAYER AG (DE) | 1980-01-23 | — | — | EP | disclosed |
| EP-0004895-A2 | Dichlorobenzodioxole derivatives, process for their preparation and their use as synergetic agents in insecticidal and acaricidal compositions | BAYER AG (DE) | 1979-10-31 | — | — | EP | disclosed |