SCHEMBL30185992

SCHEMBL30185992

c1ccc2c(c1)OC1(O2)Oc2ccccc2O1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.41
ABCG2 Q9UNQ0 1/20 0.40
ITGB2 P05107 1/20 0.40
ICAM1 P05362 1/20 0.40
ITGAL P20701 1/20 0.40
LMNA P02545 3/20 0.35
HTT P42858 3/20 0.35
CRHBP P24387 2/20 0.35
CRHR2 Q13324 2/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
MAOA P21397 2/20 0.35
MAOB P27338 2/20 0.35
AHR P35869 2/20 0.33
OPRD1 P41143 1/20 0.31
OPRK1 P41145 1/20 0.31
KCNH2 Q12809 1/20 0.31
HTR2C P28335 1/20 0.30
HTR2B P41595 1/20 0.30
MEN1 O00255 1/20 0.30
TP53 P04637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9289415 1.00 ALOX5 (0.41) ALOX5ABCG2ITGB2ICAM1ITGAL
SCHEMBL23117420 0.91 TSHR (0.41) ALOX5ABCG2ITGB2ICAM1ITGAL
SCHEMBL5951205 0.80 ABCG2 (0.43) ALOX5ABCG2ITGB2ICAM1ITGAL
SCHEMBL20756634 0.78 MAOA (0.61) ABCG2ITGB2ICAM1ITGALSMN1; SMN2
SCHEMBL13783569 0.73 HTT (0.44) ALOX5ABCG2ITGB2ICAM1ITGAL
SCHEMBL6994886 0.73 ALOX5 (0.38) ALOX5ABCG2ITGB2ICAM1ITGAL
SCHEMBL1003323 0.73 ALOX5 (0.38) ALOX5ABCG2ITGB2ICAM1ITGAL
SCHEMBL4501435 0.73 ALOX5 (0.38) ALOX5ABCG2ITGB2ICAM1ITGAL
SCHEMBL370061 0.73 TSHR (0.58) ALOX5ABCG2ITGB2ICAM1ITGAL
SCHEMBL848935 0.73 ALOX5 (0.38) ALOX5ABCG2ITGB2ICAM1ITGAL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11549020-B2 Curable composition for nano-fabrication CANON KABUSHIKI KAISHA (JP) 2023-01-10 US disclosed