Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 3/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | PDE3B | Q13370 | 4/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 4/20 | 0.40 |
| ▸ | P2RY12 | Q9H244 | 4/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | THRA | P10827 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10033249 | 0.83 | HDAC1 (0.51) | HDAC1THRBHDAC3HDAC4HDAC7 | |
| SCHEMBL495711 | 0.80 | HTT (0.36) | TSHRNPC1THRBHDAC6CYP3A4 | |
| SCHEMBL10033251 | 0.78 | TSHR (0.53) | TSHRALDH1A1CYP3A4 | |
| SCHEMBL495772 | 0.78 | TSHR (0.53) | TSHRALDH1A1CYP3A4 | |
| SCHEMBL10033259 | 0.77 | PTPN1 (0.34) | TSHRNPC1THRBHDAC6HTT | |
| SCHEMBL15302815 | 0.76 | AKR1C3 (0.44) | TSHRRAB9ATHRB | |
| SCHEMBL12604219 | 0.74 | TSHR (0.45) | HDAC1TSHRFFAR1PDE3BPDE3A | |
| SCHEMBL19845026 | 0.74 | TSHR (0.49) | TSHRTHRBALDH1A1CYP3A4 | |
| SCHEMBL12118079 | 0.74 | TSHR (0.51) | HDAC1TSHRTHRBTHRAALDH1A1 | |
| SCHEMBL3735961 | 0.74 | THRB (0.57) | HDAC1TSHRNPC1RAB9ATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8105662-B2 | Additive components for liquid crystalline materials | ROLIC AG (CH) | 2012-01-31 | — | — | US | disclosed |
| US-20070257230-A1 | Additive Components for Liquid Crystalline Materials | ROLIC AG (CH) | 2007-11-08 | — | — | US | disclosed |