Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | PRKCA | P17252 | 2/20 | 0.36 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.36 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.36 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10033251 | 1.00 | TSHR (0.53) | TSHRALDH1A1MAPTCYP3A4LMNA | |
| SCHEMBL19717885 | 0.83 | LMNA (0.49) | TSHRALDH1A1MAPTLMNAHPGD | |
| SCHEMBL17696343 | 0.80 | TSHR (0.58) | TSHRALDH1A1MAPTCYP3A4LMNA | |
| SCHEMBL2065282 | 0.80 | TSHR (0.58) | TSHRALDH1A1CYP3A4HPGD | |
| SCHEMBL8906616 | 0.80 | TSHR (0.46) | TSHRALDH1A1MAPTCYP3A4LMNA | |
| SCHEMBL23647296 | 0.80 | TSHR (0.52) | TSHRALDH1A1MAPTCYP3A4LMNA | |
| SCHEMBL19064328 | 0.79 | TSHR (0.56) | TSHRALDH1A1CYP3A4HPGD | |
| SCHEMBL8906617 | 0.79 | TSHR (0.45) | TSHRALDH1A1MAPTCYP3A4LMNA | |
| SCHEMBL13397834 | 0.78 | TSHR (0.63) | TSHRALDH1A1MAPTCYP3A4HPGD | |
| SCHEMBL10033253 | 0.78 | HDAC1 (0.42) | TSHRALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8105662-B2 | Additive components for liquid crystalline materials | ROLIC AG (CH) | 2012-01-31 | — | — | US | disclosed |
| US-8105662-B2 | Additive components for liquid crystalline materials | ROLIC AG (CH) | 2012-01-31 | — | — | US | disclosed |
| US-8105662-B2 | Additive components for liquid crystalline materials | ROLIC AG (CH) | 2012-01-31 | — | — | US | disclosed |
| EP-1689827-B1 | ADDITIVE COMPONENTS FOR LIQUID CRYSTALLINE MATERIALS | ROLIC AG (CH) | 2008-07-09 | — | — | EP | disclosed |
| EP-1689827-B1 | ADDITIVE COMPONENTS FOR LIQUID CRYSTALLINE MATERIALS | ROLIC AG (CH) | 2008-07-09 | — | — | EP | disclosed |
| US-20070257230-A1 | Additive Components for Liquid Crystalline Materials | ROLIC AG (CH) | 2007-11-08 | — | — | US | disclosed |
| US-20070257230-A1 | Additive Components for Liquid Crystalline Materials | ROLIC AG (CH) | 2007-11-08 | — | — | US | disclosed |
| US-20070257230-A1 | Additive Components for Liquid Crystalline Materials | ROLIC AG (CH) | 2007-11-08 | — | — | US | disclosed |
| EP-1689827-A1 | ADDITIVE COMPONENTS FOR LIQUID CRYSTALLINE MATERIALS | Rolic AG (CH) | 2006-08-16 | — | — | EP | disclosed |
| WO-2005054406-A1 | ADDITIVE COMPONENTS FOR LIQUID CRYSTALLINE MATERIALS | ROLIC AG (CH) | 2005-06-16 | — | — | WO | disclosed |