Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.66 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.50 |
| ▸ | RELA | Q04206 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 4/20 | 0.47 |
| ▸ | AGPAT2 | O15120 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22077654 | 0.86 | MAPT (0.47) | MAPTKDM4ERAB9ANPC1ALDH1A1 | |
| SCHEMBL9757152 | 0.86 | MAPT (0.60) | MAPTKDM4ERAB9ANPC1SMN1; SMN2 | |
| SCHEMBL22077658 | 0.85 | MAPT (0.52) | MAPTKDM4ERAB9ANPC1ALDH1A1 | |
| SCHEMBL24330809 | 0.85 | MAPT (0.71) | MAPTKDM4ERAB9ANPC1SMN1; SMN2 | |
| SCHEMBL10474999 | 0.82 | RAB9A (0.60) | MAPTKDM4ERAB9ANPC1SMN1; SMN2 | |
| SCHEMBL22077663 | 0.80 | PDE3B (0.51) | MAPTKDM4ERAB9ANPC1SMN1; SMN2 | |
| SCHEMBL11191233 | 0.79 | MAPT (0.66) | MAPTKDM4ERAB9ANPC1SMN1; SMN2 | |
| SCHEMBL14925499 | 0.77 | MAPT (0.49) | MAPTKDM4ERAB9ANPC1SMN1; SMN2 | |
| SCHEMBL23916237 | 0.77 | ALDH1A1 (0.49) | MAPTKDM4ERAB9ANPC1SMN1; SMN2 | |
| SCHEMBL5535594 | 0.76 | MAPT (0.83) | MAPTKDM4ERAB9ANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012002501-A1 | LIQUID CRYSTAL ALIGNMENT TREATMENT AGENT, LIQUID CRYSTAL ALIGNMENT FILM, AND LIQUID CRYSTAL DISPLAY ELEMENT EQUIPPED WITH THE LIQUID CRYSTAL ALIGNMENT FILM | 日産化学工業株式会社 (JP) | 2012-01-05 | — | — | WO | disclosed |