Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | PKM | P14618 | 2/20 | 0.56 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.49 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.49 |
| ▸ | MMP2 | P08253 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.46 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.46 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.46 |
| ▸ | TERT | O14746 | 2/20 | 0.46 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.45 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.45 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.45 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12085451 | 1.00 | ALDH1A1 (0.58) | ALDH1A1SMN1; SMN2PKMGRIN1GRIN2A | |
| SCHEMBL18906002 | 0.82 | ALDH1A1 (0.81) | ALDH1A1SMN1; SMN2PKMTSHRHDAC3 | |
| SCHEMBL12085474 | 0.81 | GRIN1 (0.61) | GRIN1GRIN2AMMP2GNAI3GNAO1 | |
| SCHEMBL10033846 | 0.81 | GRIN1 (0.61) | GRIN1GRIN2AMMP2GNAI3GNAO1 | |
| SCHEMBL21689911 | 0.81 | SMN1; SMN2 (0.68) | ALDH1A1SMN1; SMN2PKMTSHRHDAC3 | |
| SCHEMBL10069005 | 0.81 | SMN1; SMN2 (0.68) | ALDH1A1SMN1; SMN2PKMTSHRHDAC3 | |
| SCHEMBL24179776 | 0.79 | GNAI3 (0.69) | SMN1; SMN2PKMGRIN1GRIN2AMMP2 | |
| SCHEMBL10033848 | 0.79 | GNAI3 (0.69) | SMN1; SMN2PKMGRIN1GRIN2AMMP2 | |
| SCHEMBL12085475 | 0.79 | GNAI3 (0.69) | SMN1; SMN2PKMGRIN1GRIN2AMMP2 | |
| SCHEMBL12085568 | 0.78 | GRIN1 (0.59) | SMN1; SMN2GRIN1GRIN2AMMP2HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE43327-E1 | Hydrophobic polyamine analogs and methods for their use | AMINEX THERAPEUTICS, INC. (US) | 2012-04-24 | — | — | US | disclosed |
| US-RE43327-E1 | Hydrophobic polyamine analogs and methods for their use | AMINEX THERAPEUTICS, INC. (US) | 2012-04-24 | — | — | US | disclosed |
| US-7432302-B2 | Composition containing polyamine transport inhibitor and use thereof | MEDIQUEST THERAPEUTICS, INC. (US) | 2008-10-07 | — | — | US | disclosed |
| US-7432302-B2 | Composition containing polyamine transport inhibitor and use thereof | MEDIQUEST THERAPEUTICS, INC. (US) | 2008-10-07 | — | — | US | disclosed |