Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.68 |
| ▸ | PKM | P14618 | 2/20 | 0.68 |
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.53 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21689911 | 1.00 | SMN1; SMN2 (0.68) | SMN1; SMN2ALDH1A1PKMNPC1RAB9A | |
| SCHEMBL26057615 | 0.85 | SMN1; SMN2 (0.62) | SMN1; SMN2ALDH1A1PKMNPC1RAB9A | |
| SCHEMBL26057588 | 0.84 | SMN1; SMN2 (0.68) | SMN1; SMN2ALDH1A1PKMNPC1RAB9A | |
| SCHEMBL26057651 | 0.84 | SMN1; SMN2 (0.68) | SMN1; SMN2ALDH1A1PKMNPC1RAB9A | |
| SCHEMBL16266236 | 0.82 | SMN1; SMN2 (1.00) | SMN1; SMN2ALDH1A1PKMNPC1RAB9A | |
| SCHEMBL14996214 | 0.82 | ALDH1A1 (0.74) | SMN1; SMN2ALDH1A1PKMNPC1RAB9A | |
| SCHEMBL23099259 | 0.82 | ERCC5 (0.44) | SMN1; SMN2ALDH1A1PKMNPC1RAB9A | |
| SCHEMBL31687700 | 0.82 | ERCC5 (0.44) | SMN1; SMN2ALDH1A1PKMNPC1RAB9A | |
| SCHEMBL12085451 | 0.81 | ALDH1A1 (0.58) | SMN1; SMN2ALDH1A1PKMNPC1RAB9A | |
| SCHEMBL10033845 | 0.81 | ALDH1A1 (0.58) | SMN1; SMN2ALDH1A1PKMNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2655395-B1 | METHOD FOR CROSS-LINKING PEPTIDES | UNIV GENT (BE) | 2018-03-07 | — | — | EP | disclosed |
| US-9708363-B2 | Method for cross-linking peptides | UNIVERSITEIT GENT (BE) | 2017-07-18 | — | — | US | disclosed |
| US-9708363-B2 | Method for cross-linking peptides | UNIVERSITEIT GENT (BE) | 2017-07-18 | — | — | US | disclosed |
| US-20160244481-A1 | METHOD FOR CROSS-LINKING PEPTIDES | UNIVERSITEIT GENT (BE) | 2016-08-25 | — | — | US | disclosed |
| US-20160244481-A1 | METHOD FOR CROSS-LINKING PEPTIDES | UNIVERSITEIT GENT (BE) | 2016-08-25 | — | — | US | disclosed |
| US-9290537-B2 | Method for cross-linking peptides | UNIVERSITEIT GENT (BE) | 2016-03-22 | — | — | US | disclosed |
| US-9290537-B2 | Method for cross-linking peptides | UNIVERSITEIT GENT (BE) | 2016-03-22 | — | — | US | disclosed |
| US-20130289239-A1 | METHOD FOR CROSS-LINKING PEPTIDES | UNIVERSITEIT GENT (BE) | 2013-10-31 | — | — | US | disclosed |
| US-20130289239-A1 | METHOD FOR CROSS-LINKING PEPTIDES | UNIVERSITEIT GENT (BE) | 2013-10-31 | — | — | US | disclosed |
| WO-2012085279-A2 | METHOD FOR CROSS-LINKING PEPTIDES | UNIVERSITEIT GENT (BE) | 2012-06-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160244481-A1 | METHOD FOR CROSS-LINKING PEPTIDES | PTMS, VIP, FPR2 | SMN1; SMN2 4574/4885ALDH1A1 2712/4885PKM 3080/4885 |
| US-20130289239-A1 | METHOD FOR CROSS-LINKING PEPTIDES | PTMS, VIP, FPR2 | SMN1; SMN2 4574/4885ALDH1A1 2712/4885PKM 3080/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.