Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 3/20 | 0.60 |
| ▸ | MAOA | P21397 | 3/20 | 0.56 |
| ▸ | MAOB | P27338 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | CTSV | O60911 | 3/20 | 0.54 |
| ▸ | CTSL | P07711 | 3/20 | 0.54 |
| ▸ | NSD2 | O96028 | 1/20 | 0.54 |
| ▸ | AS3MT | Q9HBK9 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.52 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.52 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4151637 | 0.83 | TRPM8 (0.57) | TRPM8MAOAMAOBKDM4EMAPT | |
| SCHEMBL25904016 | 0.82 | TRPM8 (0.59) | TRPM8MAOAMAOBKDM4EMAPT | |
| SCHEMBL5504619 | 0.82 | KDM4E (0.69) | TRPM8MAOAMAOBKDM4EMAPT | |
| SCHEMBL29652545 | 0.82 | TRPM8 (0.56) | TRPM8MAOAMAOBKDM4EMAPT | |
| SCHEMBL102598 | 0.82 | TRPM8 (0.56) | TRPM8MAOAMAOBKDM4EMAPT | |
| SCHEMBL25904061 | 0.81 | MAOA (0.55) | TRPM8MAOAMAOBKDM4EMAPT | |
| SCHEMBL4156633 | 0.80 | TRPM8 (0.54) | TRPM8MAOAMAOBKDM4EMAPT | |
| SCHEMBL4155076 | 0.80 | TRPM8 (0.54) | TRPM8MAOAMAOBKDM4EMAPT | |
| SCHEMBL6600768 | 0.80 | TRPM8 (0.57) | TRPM8MAOAMAOBKDM4EMAPT | |
| SCHEMBL4155146 | 0.79 | TRPM8 (0.53) | TRPM8MAOAMAOBKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2426105-A1 | Process for the preparation of 5-benzyloxy-2-(4-benzyloxyphenyl)-3-methyl-1h-indole | Divi's Laboratories Limited (IN) | 2012-03-07 | — | — | EP | disclosed |
| US-7968732-B1 | Process for the preparation of 5-benzyloxy-2-(4-benzyloxyphenyl)-3-methyl-1H-indole | Divi's Laboratories, Ltd. (IN) | 2011-06-28 | — | — | US | disclosed |