Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | MAOA | P21397 | 2/20 | 0.53 |
| ▸ | MAOB | P27338 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.52 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.52 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.52 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.52 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.52 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.52 |
| ▸ | CTSV | O60911 | 3/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6600768 | 0.85 | TRPM8 (0.57) | TRPM8KDM4EMAPTHPGDHSD17B10 | |
| SCHEMBL100339 | 0.82 | TRPM8 (0.60) | TRPM8KDM4EMAPTHPGDHSD17B10 | |
| SCHEMBL28819188 | 0.82 | GABRA1 (0.59) | TRPM8KDM4EMAPTHPGDHSD17B10 | |
| SCHEMBL5504619 | 0.82 | KDM4E (0.69) | TRPM8KDM4EMAPTHPGDHSD17B10 | |
| SCHEMBL22074470 | 0.81 | TRPM8 (0.54) | TRPM8KDM4EMAPTHPGDHSD17B10 | |
| SCHEMBL4151637 | 0.80 | TRPM8 (0.57) | TRPM8KDM4EMAPTHPGDHSD17B10 | |
| SCHEMBL4155076 | 0.80 | TRPM8 (0.54) | TRPM8KDM4EMAPTHPGDHSD17B10 | |
| SCHEMBL102598 | 0.79 | TRPM8 (0.56) | TRPM8KDM4EMAPTHPGDHSD17B10 | |
| SCHEMBL29652545 | 0.79 | TRPM8 (0.56) | TRPM8KDM4EMAPTHPGDHSD17B10 | |
| SCHEMBL18222504 | 0.78 | MTNR1A (0.57) | TRPM8KDM4EMAPTHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125397-A1 | PREPARATION METHOD FOR AROMATIC RING DERIVATIVE FOR IMMUNE REGULATION | 上海济煜医药科技有限公司 | 2023-07-06 | — | — | WO | disclosed |