Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.72 |
| ▸ | P2RY1 | P47900 | 4/20 | 0.66 |
| ▸ | ENPP1 | P22413 | 3/20 | 0.66 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.63 |
| ▸ | P2RX1 | P51575 | 3/20 | 0.63 |
| ▸ | P2RX3 | P56373 | 3/20 | 0.63 |
| ▸ | P2RX2 | Q9UBL9 | 2/20 | 0.63 |
| ▸ | P2RY2 | P41231 | 2/20 | 0.60 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.60 |
| ▸ | SRC | P12931 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | DTYMK | P23919 | 2/20 | 0.60 |
| ▸ | MACROD2 | A1Z1Q3 | 1/20 | 0.57 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.57 |
| ▸ | MACROD1 | Q9BQ69 | 1/20 | 0.57 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31454757 | 0.94 | POLB (0.70) | POLBP2RY1ENPP1RNASELP2RY2 | |
| SCHEMBL29382612 | 0.94 | POLB (0.70) | POLBP2RY1ENPP1RNASELP2RY2 | |
| SCHEMBL78250 | 0.94 | POLB (0.80) | POLBP2RY1ENPP1RNASELP2RX1 | |
| SCHEMBL14471000 | 0.94 | POLB (0.80) | POLBP2RY1ENPP1RNASELP2RX1 | |
| SCHEMBL29702495 | 0.94 | POLB (0.80) | POLBP2RY1ENPP1RNASELP2RX1 | |
| SCHEMBL703733 | 0.94 | POLB (0.80) | POLBP2RY1ENPP1RNASELP2RX1 | |
| SCHEMBL18785117 | 0.94 | POLB (0.80) | POLBP2RY1ENPP1RNASELP2RX1 | |
| SCHEMBL5044161 | 0.94 | POLB (0.80) | POLBP2RY1ENPP1RNASELP2RX1 | |
| SCHEMBL889289 | 0.94 | POLB (0.80) | POLBP2RY1ENPP1RNASELP2RX1 | |
| SCHEMBL29350133 | 0.94 | POLB (0.80) | POLBP2RY1ENPP1RNASELP2RX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120053226-A1 | DESIGN OF OLIGONUCLEOTIDE ANALOGS AS THERAPEUTIC AGENTS | SPRING BANK PHARMACEUTICALS, INC. (US) | 2012-03-01 | — | — | US | disclosed |
| US-20120053226-A1 | DESIGN OF OLIGONUCLEOTIDE ANALOGS AS THERAPEUTIC AGENTS | SPRING BANK PHARMACEUTICALS, INC. (US) | 2012-03-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120053226-A1 | DESIGN OF OLIGONUCLEOTIDE ANALOGS AS THERAPEUTIC AGENTS | TLR3, TLR5, TLR9 | POLB 327/4885P2RY1 101/4885ENPP1 122/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.