Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.70 |
| ▸ | ENPP1 | P22413 | 3/20 | 0.66 |
| ▸ | P2RY1 | P47900 | 2/20 | 0.66 |
| ▸ | RNASEL | Q05823 | 3/20 | 0.61 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.60 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.60 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.60 |
| ▸ | LDHA | P00338 | 1/20 | 0.60 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.60 |
| ▸ | FBP1 | P09467 | 1/20 | 0.60 |
| ▸ | SRC | P12931 | 1/20 | 0.60 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.60 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.60 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.60 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.60 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.60 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.60 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.60 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31454757 | 1.00 | POLB (0.70) | POLBENPP1P2RY1RNASELDNPH1 | |
| SCHEMBL10034040 | 0.94 | POLB (0.72) | POLBENPP1P2RY1RNASELTRPM2 | |
| SCHEMBL24864688 | 0.94 | POLB (0.69) | POLBENPP1P2RY1RNASELADORA1 | |
| SCHEMBL29519602 | 0.94 | POLB (0.69) | POLBENPP1P2RY1RNASELADORA1 | |
| SCHEMBL11927745 | 0.92 | POLB (0.81) | POLBENPP1P2RY1RNASELDNPH1 | |
| SCHEMBL7882477 | 0.92 | POLB (0.81) | POLBENPP1P2RY1RNASELDNPH1 | |
| SCHEMBL4546151 | 0.92 | POLB (0.81) | POLBENPP1P2RY1RNASELDNPH1 | |
| SCHEMBL18785113 | 0.92 | POLB (0.81) | POLBENPP1P2RY1RNASELDNPH1 | |
| SCHEMBL543475 | 0.92 | POLB (0.81) | POLBENPP1P2RY1RNASELDNPH1 | |
| SCHEMBL48174 | 0.92 | POLB (0.81) | POLBENPP1P2RY1RNASELDNPH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 199 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4652271-A1 | BASE EDITING-MEDIATED READTHROUGH OF PREMATURE TERMINATION CODONS (BERT) | The Broad Institute, Inc. (US) | 2025-11-26 | — | — | EP | claimed |
| CN-120153077-A | Novel CRISPR/Cas system | 斯尼普生物群系有限公司 | 2025-06-13 | — | — | CN | claimed |
| US-12264330-B2 | Recombinant type I CRISPR-Cas system and uses thereof for killing target cells | NORTH CAROLINA STATE UNIVERSITY (US) | 2025-04-01 | — | — | US | claimed |
| US-12264313-B2 | Recombinant type I CRISPR-Cas system and uses thereof for genome modification and alteration of expression | NORTH CAROLINA STATE UNIVERSITY (US) | 2025-04-01 | — | — | US | claimed |
| CN-119709757-A | SgRNA and CRISPR/FpCas gene editing system and application thereof | 中国水产科学研究院黑龙江水产研究所 | 2025-03-28 | — | — | CN | claimed |
| WO-2025054355-A1 | METHODS, SYSTEMS, AND COMPOSITIONS FOR EXOGENOUS CONTROL OF PROTEIN EXPRESSION | RADAR THERAPEUTICS INC. (US) | 2025-03-13 | — | — | WO | claimed |
| US-12247200-B2 | Compositions and methods for generating massively parallel nucleic acid sequencing libraries | BIOO SCIENTIFIC CORPORATION (US) | 2025-03-11 | — | — | US | claimed |
| US-12203123-B2 | Recombinant type I CRISPR-Cas system and uses thereof for screening for variant cells | NORTH CAROLINA STATE UNIVERSITY (US) | 2025-01-21 | — | — | US | claimed |
| US-20240254479-A1 | ENGINEERED GUIDE RNA FOR OPTIMIZED CRISPR/CAS12F1 SYSTEM AND USE THEREOF | GENKORE INC. (KR) | 2024-08-01 | — | — | US | claimed |
| WO-2024155745-A1 | BASE EDITING-MEDIATED READTHROUGH OF PREMATURE TERMINATION CODONS (BERT) | THE BROAD INSTITUTE, INC. (US) | 2024-07-25 | — | — | WO | claimed |
| US-20230016656-A1 | NOVEL CRISPR DNA TARGETING ENZYMES AND SYSTEMS | Arbor Biotechnologies, Inc. | 2023-01-19 | — | — | US | claimed |
| WO-2022241270-A2 | COMPOSITIONS AND METHODS FOR TREATING TRANSTHYRETIN AMYLOIDOSIS | BEAM THERAPEUTICS INC. (US) | 2022-11-17 | — | — | WO | claimed |
| WO-2022220503-A1 | GENE EXPRESSION REGULATORY SYSTEM USING CRISPR SYSTEM | 주식회사 진코어 | 2022-10-20 | — | — | WO | claimed |
| EP-4021924-A1 | NOVEL CRISPR DNA TARGETING ENZYMES AND SYSTEMS | Arbor Biotechnologies, Inc. (US) | 2022-07-06 | — | — | EP | claimed |
| US-20220177943-A1 | RECOMBINANT TYPE I CRISPR-CAS SYSTEM AND USES THEREOF FOR SCREENING FOR VARIANT CELLS | NORTH CAROLINA STATE UNIVERSITY | 2022-06-09 | — | — | US | claimed |
| US-20220170048-A1 | RECOMBINANT TYPE I CRISPR-CAS SYSTEM AND USES THEREOF FOR KILLING TARGET CELLS | NORTH CAROLINA STATE UNIVERSITY | 2022-06-02 | — | — | US | claimed |
| WO-2022075816-A1 | ENGINEERED GUIDE RNA FOR INCREASING EFFICIENCY OF CRISPR/CAS12F1 (CAS14A1) SYSTEM, AND USE THEREOF | 주식회사 진코어 | 2022-04-14 | — | — | WO | claimed |
| WO-2022075808-A1 | ENGINEERED GUIDE RNA COMPRISING U-RICH TAIL FOR INCREASING EFFICIENCY OF CRISPR/CAS12F1 SYSTEM, AND USE THEREOF | 주식회사 진코어 | 2022-04-14 | — | — | WO | claimed |
| WO-2022075813-A1 | ENGINEERED GUIDE RNA FOR INCREASING EFFICIENCY OF CRISPR/CAS12F1 SYSTEM, AND USE OF SAME | 주식회사 진코어 | 2022-04-14 | — | — | WO | claimed |
| EP-3965832-A1 | COMPOSITIONS AND METHODS FOR TREATING HEPATITIS B | Beam Therapeutics, Inc. (US) | 2022-03-16 | — | — | EP | claimed |