Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | HTR2B | P41595 | 3/20 | 0.35 |
| ▸ | HTR2C | P28335 | 2/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 2/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.31 |
| ▸ | HTR5A | P47898 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | HRH2 | P25021 | 1/20 | 0.31 |
| ▸ | HTR7 | P34969 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21097485 | 0.77 | SRD5A1 (0.40) | HTR2BHTR2CALDH1A1SMN1; SMN2DRD4 | |
| SCHEMBL10001710 | 0.71 | ALOX12 (0.36) | ALOX12GAAHTR2BHTR2CCNR2 | |
| SCHEMBL10110283 | 0.71 | ALOX12 (0.36) | ALOX12GAAHTR2BHTR2CCNR2 | |
| SCHEMBL12085764 | 0.71 | ALOX12 (0.36) | ALOX12GAAHTR2BHTR2CCNR2 | |
| SCHEMBL10034154 | 0.67 | GAA (0.31) | GAA | |
| SCHEMBL2625804 | 0.66 | ALOX12 (0.50) | ALOX12GAAHTR2BHTR2CCNR2 | |
| SCHEMBL8555101 | 0.66 | SRD5A1 (0.46) | ALOX12HTR2BHTR2CCNR2ALDH1A1 | |
| SCHEMBL14281834 | 0.65 | ALOX12 (0.45) | ALOX12GAAHTR2BHTR2CCNR2 | |
| SCHEMBL14281840 | 0.63 | GAA (0.49) | ALOX12GAAHTR2BHTR2CCNR2 | |
| SCHEMBL12905298 | 0.63 | ALOX12 (0.47) | ALOX12GAAHTR2BHTR2CCNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8426041-B2 | Carbene metal complexes as OLED materials | UNIVERSAL DISPLAY CORPORATION (US) | 2013-04-23 | — | — | US | disclosed |
| US-20120104378-A1 | CARBENE METAL COMPLEXES AS OLED MATERIALS | DJUROVICH PETER (US) | 2012-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120104378-A1 | CARBENE METAL COMPLEXES AS OLED MATERIALS | OCIAD1, OCIAD2, OXA1L | ALOX12 157/4885GAA 4304/4885HTR2B 3381/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.