Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 2/20 | 0.35 |
| ▸ | HTR2B | P41595 | 2/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 2/20 | 0.30 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | DRD4 | P21917 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12085764 | 1.00 | ALOX12 (0.36) | ALOX12HTR2CHTR2BHTR2ACNR2 | |
| SCHEMBL10001710 | 1.00 | ALOX12 (0.36) | ALOX12HTR2CHTR2BHTR2ACNR2 | |
| SCHEMBL18120574 | 0.77 | SLC6A2 (0.39) | HTR2CHTR2BHTR2ASLC6A2SLC6A3 | |
| SCHEMBL16709143 | 0.72 | ALOX12 (0.40) | ALOX12HTR2CHTR2BHTR2ACNR2 | |
| SCHEMBL10034155 | 0.71 | ALOX12 (0.39) | ALOX12HTR2CHTR2BHTR2ACNR2 | |
| SCHEMBL10110280 | 0.66 | — | — | |
| SCHEMBL12436168 | 0.66 | — | — | |
| SCHEMBL13731873 | 0.64 | GAA (0.43) | ALOX12HTR2CHTR2BHTR2ACNR2 | |
| SCHEMBL13875974 | 0.64 | ALDH1A1 (0.39) | ALOX12HTR2CHTR2BHTR2AGAA | |
| SCHEMBL13875971 | 0.64 | HTR2C (0.35) | ALOX12HTR2CHTR2BHTR2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2205615-B1 | TRANSITION METAL COMPLEXES WITH BRIDGED CARBENE LIGANDS AND USE THEREOF IN OLEDS | BASF SE (DE) | 2012-04-18 | — | — | EP | disclosed |