SCHEMBL10034190

SCHEMBL10034190

Cc1nc(C)nc(N(c2ccccc2)c2ccc(-c3ccc4ccc5cc6c(c7ccc3c4c57)c3ccccc3n6-c3ccccc3)cc2)n1

nearest known ligand 0.32

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ L3MBTL1 Q9Y468 2/20 0.32
▸ KDM4E B2RXH2 2/20 0.32
▸ ATM Q13315 1/20 0.32
▸ MAPT P10636 2/20 0.30
▸ MEN1 O00255 1/20 0.30
▸ XBP1 P17861 1/20 0.30
▸ MAPK1 P28482 1/20 0.30
▸ NTSR1 P30989 1/20 0.30
▸ KMT2A Q03164 1/20 0.30
▸ SMN1; SMN2 Q16637 1/20 0.30
▸ NPSR1 Q6W5P4 1/20 0.30
▸ ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2601517 1.00 L3MBTL1 (0.32) L3MBTL1KDM4EATMMAPTMEN1
SCHEMBL10034187 0.89 KDM4E (0.33) L3MBTL1KDM4EATM
SCHEMBL2601512 0.89 KDM4E (0.33) L3MBTL1KDM4EATM
SCHEMBL2601475 0.89 KDM4E (0.38) L3MBTL1KDM4EATM
SCHEMBL10034160 0.89 KDM4E (0.38) L3MBTL1KDM4EATM
SCHEMBL14460414 0.89 L3MBTL1 (0.32) L3MBTL1KDM4EATMMAPTMEN1
SCHEMBL2601507 0.89 KDM4E (0.32) L3MBTL1KDM4EATM
SCHEMBL14460277 0.89 L3MBTL1 (0.32) L3MBTL1KDM4EATMMAPTMEN1
SCHEMBL10034192 0.89 KDM4E (0.32) L3MBTL1KDM4EATM
SCHEMBL10034203 0.88 KDM4E (0.37) L3MBTL1KDM4EATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8455867-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2013-06-04 — — US disclosed
US-8455867-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2013-06-04 — — US disclosed
US-8405074-B2 — — 2013-03-26 — — US disclosed
US-8405074-B2 — — 2013-03-26 — — US disclosed
US-20120097924-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG MOBILE DISPLAY CO., LTD. (KR) 2012-04-26 — — US disclosed
US-20120097924-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG MOBILE DISPLAY CO., LTD. (KR) 2012-04-26 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120097924-A1 ORGANIC LIGHT-EMITTING DEVICE KCNT1, KCNA1, TRPA1 L3MBTL1 1115/4885KDM4E 1280/4885ATM 3573/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback