SCHEMBL10034370

SCHEMBL10034370

CC1(C)c2cc(-c3ccccc3)ccc2-c2ccc(N(c3ccc4c(c3)C(C)(C)c3cc(-c5cc6ccccc6c6ccccc56)ccc3-4)c3ccc4ccccc4c3)cc21

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP11B1 P15538 1/20 0.34
GPR84 Q9NQS5 3/20 0.34
LPL P06858 1/20 0.32
LIPG Q9Y5X9 1/20 0.32
PDK2 Q15119 1/20 0.32
ACACA Q13085 1/20 0.31
KDM4E B2RXH2 1/20 0.31
MEN1 O00255 1/20 0.31
ALDH1A1 P00352 1/20 0.31
MAPT P10636 1/20 0.31
HPGD P15428 1/20 0.31
MPI P34949 1/20 0.31
KMT2A Q03164 1/20 0.31
CHRNA1 P02708 1/20 0.30
CHRNG P07510 1/20 0.30
CHRNB1 P11230 1/20 0.30
CHRNB2 P17787 1/20 0.30
SLC6A2 P23975 1/20 0.30
CHRNB4 P30926 1/20 0.30
SLC6A4 P31645 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17243489 0.96 GPR84 (0.33) CYP11B1GPR84LPLLIPGPDK2
SCHEMBL17243534 0.96 GPR84 (0.35) CYP11B1GPR84LPLLIPGALDH1A1
SCHEMBL10034325 0.95 CYP11B1 (0.37) CYP11B1GPR84PDK2ACACAKDM4E
SCHEMBL10034360 0.95 CYP11B1 (0.37) CYP11B1GPR84PDK2ACACAKDM4E
SCHEMBL10034378 0.95 CYP11B1 (0.34) CYP11B1GPR84ALDH1A1HPGDSLC6A2
SCHEMBL10034425 0.94 LPL (0.34) CYP11B1GPR84LPLLIPGPDK2
SCHEMBL17243493 0.94 GPR84 (0.33) CYP11B1GPR84LPLLIPGPDK2
SCHEMBL17243485 0.94 GPR84 (0.36) CYP11B1GPR84LPLLIPGALDH1A1
SCHEMBL17243490 0.94 GPR84 (0.36) CYP11B1GPR84LPLLIPGALDH1A1
SCHEMBL17243438 0.94 GPR84 (0.36) CYP11B1GPR84LPLLIPGALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8980442-B2 Aromatic amine derivative and organic electroluminescent element using same MITSUI CHEMICALS, INC. (JP) 2015-03-17 US disclosed
US-8980442-B2 Aromatic amine derivative and organic electroluminescent element using same MITSUI CHEMICALS, INC. (JP) 2015-03-17 US disclosed
US-20120012832-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME MITSUI CHEMICALS, INC. (JP) 2012-01-19 US disclosed
US-20120012832-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME MITSUI CHEMICALS, INC. (JP) 2012-01-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120012832-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME MAOA, MAOB, TYR CYP11B1 1963/4885GPR84 3453/4885LPL 1699/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.