Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HB | P07237 | 11/20 | 0.55 |
| ▸ | AURKA | O14965 | 2/20 | 0.55 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.55 |
| ▸ | BACE1 | P56817 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | RECQL | P46063 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MAOA | P21397 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | USP2 | O75604 | 2/20 | 0.50 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10034772 | 0.88 | MAPT (0.55) | P4HBAURKAAURKBBACE1MAPT | |
| SCHEMBL16938333 | 0.77 | BACE1 (0.57) | P4HBAURKAAURKBBACE1MAPT | |
| SCHEMBL4196479 | 0.76 | MEN1 (0.49) | BACE1MAPTKMT2AMAOAUSP2 | |
| SCHEMBL29715761 | 0.76 | STAT3 (0.58) | P4HBAURKAAURKBBACE1MAPT | |
| SCHEMBL10034767 | 0.76 | MAOA (0.60) | P4HBAURKAAURKBMAPTKDM4E | |
| SCHEMBL16879551 | 0.75 | P4HB (0.64) | P4HBAURKAAURKBBACE1MAPT | |
| Hydrochloric Acid SCHEMBL4120194 | 0.75 | MEN1 (0.47) | BACE1MAPTKMT2AMAOAUSP2 | |
| SCHEMBL10034769 | 0.75 | P4HB (0.70) | P4HBAURKAAURKBBACE1MAPT | |
| SCHEMBL16453600 | 0.75 | P4HB (0.51) | P4HBAURKAAURKBBACE1MAPT | |
| SCHEMBL5175867 | 0.74 | MAPT (0.72) | P4HBAURKAAURKBBACE1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012004543-A1 | DEVICE FOR DETECTING MOLECULES OF INTEREST, ITS MANUFACTURING PROCESS AND ITS USE | UNIVERSITE PARIS DIDEROT-PARIS 7 (FR) | 2012-01-12 | — | — | WO | disclosed |