Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HB | P07237 | 14/20 | 0.70 |
| ▸ | STAT3 | P40763 | 1/20 | 0.60 |
| ▸ | AURKA | O14965 | 1/20 | 0.51 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.51 |
| ▸ | S100A4 | P26447 | 1/20 | 0.49 |
| ▸ | BACE1 | P56817 | 1/20 | 0.48 |
| ▸ | PDIA4 | P13667 | 1/20 | 0.47 |
| ▸ | PDIA3 | P30101 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4812624 | 0.82 | P4HB (0.77) | P4HBSTAT3AURKAAURKB | |
| SCHEMBL14021570 | 0.81 | P4HB (0.75) | P4HBSTAT3AURKAAURKB | |
| SCHEMBL9180439 | 0.80 | CDC25B (0.67) | P4HBSTAT3AURKAAURKBS100A4 | |
| SCHEMBL10034852 | 0.79 | STAT3 (0.60) | P4HBSTAT3AURKAAURKBS100A4 | |
| SCHEMBL16884397 | 0.79 | SOAT1 (0.71) | STAT3S100A4 | |
| SCHEMBL10034768 | 0.75 | P4HB (0.55) | P4HBSTAT3AURKAAURKBBACE1 | |
| SCHEMBL17249988 | 0.74 | P4HB (0.81) | P4HBAURKAAURKBBACE1KDM4E | |
| SCHEMBL14021481 | 0.73 | P4HB (0.80) | P4HBAURKAAURKBBACE1KDM4E | |
| SCHEMBL16879551 | 0.72 | P4HB (0.64) | P4HBSTAT3AURKAAURKBBACE1 | |
| SCHEMBL5175867 | 0.71 | MAPT (0.72) | P4HBSTAT3AURKAAURKBBACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012004543-A1 | DEVICE FOR DETECTING MOLECULES OF INTEREST, ITS MANUFACTURING PROCESS AND ITS USE | UNIVERSITE PARIS DIDEROT-PARIS 7 (FR) | 2012-01-12 | — | — | WO | disclosed |