Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP4 | P15090 | 3/20 | 0.49 |
| ▸ | FABP5 | Q01469 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | GLA | P06280 | 2/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CSF1R | P07333 | 1/20 | 0.39 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | FABP3 | P05413 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL31522113 | 0.80 | SLC6A4 (0.46) | KDM4EALDH1A1HSD17B10HPGDMAPT | |
| SCHEMBL12611485 | 0.77 | RORA (0.46) | KDM4EALDH1A1HSD17B10HPGDMAPT | |
| SCHEMBL12611451 | 0.77 | SLC6A4 (0.53) | KDM4EALDH1A1HPGDTDP1 | |
| SCHEMBL21027020 | 0.73 | GLA (0.41) | KDM4EALDH1A1HSD17B10HPGDMAPT | |
| SCHEMBL10035122 | 0.72 | ABCB1 (0.34) | FABP4FABP5KDM4EALDH1A1HSD17B10 | |
| SCHEMBL21027113 | 0.72 | GLA (0.40) | KDM4EALDH1A1HSD17B10HPGDMAPT | |
| SCHEMBL14160798 | 0.71 | RORA (0.45) | KDM4EALDH1A1HSD17B10HPGDMAPT | |
| SCHEMBL355352 | 0.70 | FABP4 (0.82) | FABP4FABP5MAPTSMN1; SMN2TP53 | |
| SCHEMBL1415580 | 0.69 | KDM4E (0.55) | FABP4FABP5KDM4EALDH1A1HSD17B10 | |
| SCHEMBL1415802 | 0.69 | FABP4 (0.64) | FABP4FABP5ALDH1A1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9651490-B2 | Amine-substituted tricyclic fluorescent dyes | ATTO-TEC GMBH (DE) | 2017-05-16 | — | — | US | disclosed |
| US-9651490-B2 | Amine-substituted tricyclic fluorescent dyes | ATTO-TEC GMBH (DE) | 2017-05-16 | — | — | US | disclosed |
| EP-2630195-B1 | NEW AMINE-SUBSTITUTED TRICYCLIC FLUORESCENT DYES | ATTO TEC GMBH (DE) | 2016-08-17 | — | — | EP | disclosed |
| US-20130224871-A1 | Novel Amine-Substituted Tricyclic Fluorescent Dyes | ATTO-TEC GMBH (DE) | 2013-08-29 | — | — | US | disclosed |
| US-20130224871-A1 | Novel Amine-Substituted Tricyclic Fluorescent Dyes | ATTO-TEC GMBH (DE) | 2013-08-29 | — | — | US | disclosed |
| WO-2012052435-A1 | NOVEL AMINE-SUBSTITUTED TRICYCLIC FLUORESCENT DYES | ATTO-TEC GMBH (DE) | 2012-04-26 | — | — | WO | disclosed |