Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 known ✓ | P31645 | 2/20 | 0.46 |
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.46 |
| ▸ | PSEN1 known ✓ | P49768 | 13/20 | 0.42 |
| ▸ | PSEN2 known ✓ | P49810 | 13/20 | 0.42 |
| ▸ | APH1B known ✓ | Q8WW43 | 13/20 | 0.42 |
| ▸ | NCSTN known ✓ | Q92542 | 13/20 | 0.42 |
| ▸ | APH1A known ✓ | Q96BI3 | 13/20 | 0.42 |
| ▸ | PSENEN known ✓ | Q9NZ42 | 13/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12611485 | 0.86 | RORA (0.46) | SLC6A4SLC6A2HRH1KDM4EALDH1A1 | |
| SCHEMBL12611451 | 0.86 | SLC6A4 (0.53) | SLC6A4SLC6A2HRH1KDM4EALDH1A1 | |
| SCHEMBL14160798 | 0.81 | RORA (0.45) | SLC6A4SLC6A2HRH1KDM4EALDH1A1 | |
| SCHEMBL22042198 | 0.81 | PSEN1 (0.50) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL10035151 | 0.80 | FABP4 (0.49) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL14493937 | 0.75 | SLC6A4 (0.63) | SLC6A4SLC6A2HRH1KDM4EALDH1A1 | |
| SCHEMBL14493934 | 0.75 | SLC6A4 (0.63) | SLC6A4SLC6A2HRH1KDM4EALDH1A1 | |
| SCHEMBL8004097 | 0.74 | KDM4E (0.43) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL12657613 | 0.74 | SLC6A4 (0.70) | SLC6A4SLC6A2HRH1KDM4EALDH1A1 | |
| SCHEMBL13899719 | 0.74 | SLC6A4 (0.48) | SLC6A4SLC6A2HRH1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113227752-B | Enhanced, rapid, homogeneous cell staining and assay | 上海宜晟生物科技有限公司 | 2025-04-29 | — | — | CN | disclosed |