Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 14/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | GLA | P06280 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | MTOR | P42345 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14963236 | 0.85 | KDM4E (0.50) | KDM4EALDH1A1HTTMEN1GLA | |
| SCHEMBL10035458 | 0.84 | KDM4E (0.55) | KDM4EALDH1A1HTTMEN1GLA | |
| SCHEMBL10001054 | 0.76 | ALDH1A1 (0.54) | KDM4EALDH1A1HTTMEN1GLA | |
| SCHEMBL11198627 | 0.74 | KDM4E (0.51) | KDM4EALDH1A1HTTMEN1GLA | |
| SCHEMBL432202 | 0.74 | KDM4E (0.66) | KDM4EALDH1A1HTTMEN1GLA | |
| SCHEMBL3323518 | 0.72 | GAA (1.00) | KDM4EALDH1A1HTTMEN1GLA | |
| SCHEMBL10001052 | 0.72 | ADORA3 (0.49) | KDM4EALDH1A1HTTMEN1GLA | |
| SCHEMBL434624 | 0.70 | KDM4E (0.80) | KDM4EALDH1A1HTTMEN1GLA | |
| SCHEMBL10001049 | 0.70 | KDM4E (0.58) | KDM4EALDH1A1HTTMEN1KMT2A | |
| SCHEMBL1007130 | 0.70 | ALDH1A1 (0.73) | KDM4EALDH1A1HTTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130131126-A1 | DERIVATIVES OF 1,4-DIHYDROPYRIDINE POSSESSING ANTIVIRAL EFFICACY | JSC GRINDEKS (LV) | 2013-05-23 | — | — | US | disclosed |
| US-20130131126-A1 | DERIVATIVES OF 1,4-DIHYDROPYRIDINE POSSESSING ANTIVIRAL EFFICACY | JSC GRINDEKS (LV) | 2013-05-23 | — | — | US | disclosed |
| WO-2012010276-A1 | DERIVATIVES OF 1,4-DIHYDROPYRIDINE POSSESSING ANTIVIRAL EFFICACY | GRINDEKS (LV) | 2012-01-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130131126-A1 | DERIVATIVES OF 1,4-DIHYDROPYRIDINE POSSESSING ANTIVIRAL EFFICACY | IFNAR1, SARS1, MAVS | KDM4E 43/4885ALDH1A1 349/4885HTT 2823/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.