Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.81 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10126971 | 0.85 | ALDH1A1 (0.58) | HTTALDH1A1CYP3A4CYP2C19SMN1; SMN2 | |
| SCHEMBL29354408 | 0.85 | ALDH1A1 (0.58) | HTTALDH1A1CYP3A4CYP2C19SMN1; SMN2 | |
| SCHEMBL16305330 | 0.82 | ALDH1A1 (0.67) | HTTALDH1A1CYP3A4CYP2C19SMN1; SMN2 | |
| SCHEMBL30464729 | 0.80 | ALDH1A1 (0.59) | HTTALDH1A1CYP3A4CYP2C19SMN1; SMN2 | |
| SCHEMBL10036442 | 0.80 | ALDH1A1 (0.59) | HTTALDH1A1CYP3A4CYP2C19SMN1; SMN2 | |
| SCHEMBL30464731 | 0.78 | WDR5 (0.49) | HTTALDH1A1CYP3A4CYP2C19SMN1; SMN2 | |
| SCHEMBL328462 | 0.78 | WDR5 (0.49) | HTTALDH1A1CYP3A4CYP2C19SMN1; SMN2 | |
| SCHEMBL28685655 | 0.77 | HTT (0.48) | HTTALDH1A1CYP3A4CYP2C19SMN1; SMN2 | |
| SCHEMBL29399636 | 0.77 | HTT (0.48) | HTTALDH1A1CYP3A4CYP2C19SMN1; SMN2 | |
| SCHEMBL22471238 | 0.77 | ALDH1A1 (0.57) | HTTALDH1A1CYP3A4CYP2C19SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012053606-A1 | ARYLAMINOHETEROCYCLIC CARBOXAMIDE COMPOUND | アステラス製薬株式会社 (JP) | 2012-04-26 | — | — | WO | disclosed |