Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.58 |
| ▸ | HTT | P42858 | 3/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.50 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29354408 | 1.00 | ALDH1A1 (0.58) | ALDH1A1CYP1A2CYP3A4CYP2C19HTT | |
| SCHEMBL16305330 | 0.89 | ALDH1A1 (0.67) | ALDH1A1CYP1A2CYP3A4CYP2C19HTT | |
| SCHEMBL10035914 | 0.85 | HTT (0.81) | ALDH1A1CYP1A2CYP3A4CYP2C19HTT | |
| SCHEMBL328462 | 0.84 | WDR5 (0.49) | ALDH1A1CYP1A2CYP3A4CYP2C19HTT | |
| SCHEMBL30464731 | 0.84 | WDR5 (0.49) | ALDH1A1CYP1A2CYP3A4CYP2C19HTT | |
| SCHEMBL10036442 | 0.84 | ALDH1A1 (0.59) | ALDH1A1CYP1A2CYP3A4CYP2C19HTT | |
| SCHEMBL30464729 | 0.84 | ALDH1A1 (0.59) | ALDH1A1CYP1A2CYP3A4CYP2C19HTT | |
| SCHEMBL10036125 | 0.83 | ALDH1A1 (0.49) | ALDH1A1CYP1A2CYP3A4CYP2C19HTT | |
| SCHEMBL30310802 | 0.83 | ALDH1A1 (0.50) | ALDH1A1CYP1A2CYP3A4CYP2C19HTT | |
| SCHEMBL22471238 | 0.83 | ALDH1A1 (0.57) | ALDH1A1CYP1A2CYP3A4CYP2C19HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116323562-B | Compounds with kinase inhibitory activity | 上海赛岚生物科技有限公司 | 2024-06-21 | — | — | CN | disclosed |
| US-20230339936-A1 | COMPOUND HAVING KINASE INHIBITORY ACTIVITY | CYTOSINLAB THERAPEUTICS CO., LTD. (CN) | 2023-10-26 | — | — | US | disclosed |
| US-20230339936-A1 | COMPOUND HAVING KINASE INHIBITORY ACTIVITY | CYTOSINLAB THERAPEUTICS CO., LTD. (CN) | 2023-10-26 | — | — | US | disclosed |
| CN-113968856-B | Compounds with kinase inhibitory activity | 上海赛岚生物科技有限公司 | 2023-09-26 | — | — | CN | disclosed |
| CN-116323562-A | Compounds with kinase inhibitory activity | 上海赛岚生物科技有限公司 | 2023-06-23 | — | — | CN | disclosed |
| EP-4186901-A1 | COMPOUND HAVING KINASE INHIBITORY ACTIVITY | Cytosinlab Therapeutics Co., Ltd. (CN) | 2023-05-31 | — | — | EP | disclosed |
| WO-2022017434-A1 | COMPOUND HAVING KINASE INHIBITORY ACTIVITY | 上海赛岚生物科技有限公司 | 2022-01-27 | — | — | WO | disclosed |
| CN-113968856-A | Compounds with kinase inhibition activity | 上海赛岚生物科技有限公司 | 2022-01-25 | — | — | CN | disclosed |
| US-9487491-B2 | Diamino heterocyclic carboxamide compound | ASTELLAS PHARMA INC. (JP) | 2016-11-08 | — | — | US | disclosed |
| US-8969336-B2 | Diamino heterocyclic carboxamide compound | ASTELLAS PHARMA INC. (JP) | 2015-03-03 | — | — | US | disclosed |
| US-20140371196-A1 | DIAMINO HETEROCYCLIC CARBOXAMIDE COMPOUND | ASTELLAS PHARMA INC. (JP) | 2014-12-18 | — | — | US | disclosed |
| US-20120040968-A1 | DIAMINO HETEROCYCLIC CARBOXAMIDE COMPOUND | WATERS TECHNOLOGIES CORPORATION (US) | 2012-02-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140371196-A1 | DIAMINO HETEROCYCLIC CARBOXAMIDE COMPOUND | EML4, ALK, ERBB4 | ALDH1A1 1554/4885CYP1A2 4614/4885CYP3A4 3570/4885 |
| US-20230339936-A1 | COMPOUND HAVING KINASE INHIBITORY ACTIVITY | FLT3, ERBB2, ABL1 | ALDH1A1 2716/4885CYP1A2 2418/4885CYP3A4 2393/4885 |
| US-20120040968-A1 | DIAMINO HETEROCYCLIC CARBOXAMIDE COMPOUND | EML4, ALK, ERBB4 | ALDH1A1 1554/4885CYP1A2 4614/4885CYP3A4 3570/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.