Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.50 |
| ▸ | MEN1 | O00255 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | USP2 | O75604 | 4/20 | 0.50 |
| ▸ | CRHBP | P24387 | 3/20 | 0.50 |
| ▸ | CRHR2 | Q13324 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | BCHE | P06276 | 3/20 | 0.43 |
| ▸ | IDE | P14735 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | DHODH | Q02127 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13739485 | 0.76 | MAPT (0.49) | MAPTMEN1KMT2AUSP2CRHBP | |
| SCHEMBL10036074 | 0.75 | MAPT (0.61) | MAPTMEN1KMT2AUSP2CRHBP | |
| SCHEMBL13588672 | 0.75 | MAPT (0.46) | MAPTMEN1KMT2AUSP2CRHBP | |
| SCHEMBL14596636 | 0.75 | MAPT (0.50) | MAPTMEN1KMT2AUSP2CRHBP | |
| SCHEMBL13751321 | 0.74 | MAPT (0.52) | MAPTMEN1KMT2AUSP2CRHBP | |
| SCHEMBL13739774 | 0.74 | BCHE (0.45) | MAPTMEN1KMT2AUSP2CRHBP | |
| SCHEMBL10092174 | 0.74 | PDF (0.47) | MAPTMEN1KMT2AUSP2CRHBP | |
| SCHEMBL12588731 | 0.73 | BCHE (0.43) | MAPTMEN1KMT2AUSP2CRHBP | |
| SCHEMBL13739499 | 0.72 | BCHE (0.43) | MAPTMEN1KMT2AUSP2CRHBP | |
| SCHEMBL13739366 | 0.72 | PDF (0.43) | MAPTMEN1KMT2AUSP2CRHBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120035187-A1 | ANTI-NEURODEGENERATIVE DISEASE AGENT | KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) | 2012-02-09 | — | — | US | disclosed |
| US-20120035187-A1 | ANTI-NEURODEGENERATIVE DISEASE AGENT | KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) | 2012-02-09 | — | — | US | disclosed |
| US-20080193700-A1 | Metal Chelates and Their Use in Optical Recording Media Having High Storage Capacity | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2008-08-14 | — | — | US | disclosed |
| US-20080193700-A1 | Metal Chelates and Their Use in Optical Recording Media Having High Storage Capacity | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2008-08-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120035187-A1 | ANTI-NEURODEGENERATIVE DISEASE AGENT | SNCA, PSEN1, CDR2 | MAPT 43/4885MEN1 2218/4885KMT2A 2624/4885 |
| US-20080193700-A1 | Metal Chelates and Their Use in Optical Recording Media Having High Storage Capacity | TMCO1, KCNN3, CACNA1F | MAPT 580/4885MEN1 1266/4885KMT2A 1554/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.