Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | FGFR3 | P22607 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | WDR5 | P61964 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10127604 | 0.91 | ALDH1A1 (0.45) | MAPTALDH1A1KDM4EFGFR3LMNA | |
| SCHEMBL10036430 | 0.89 | FGFR3 (0.47) | MAPTALDH1A1KDM4EFGFR3LMNA | |
| SCHEMBL30736225 | 0.89 | ALDH1A1 (0.52) | MAPTALDH1A1KDM4ELMNASMN1; SMN2 | |
| SCHEMBL21808580 | 0.89 | ALDH1A1 (0.52) | MAPTALDH1A1KDM4ELMNASMN1; SMN2 | |
| SCHEMBL10036436 | 0.88 | ALDH1A1 (0.52) | MAPTALDH1A1KDM4EFGFR3LMNA | |
| SCHEMBL30306155 | 0.88 | ALDH1A1 (0.52) | MAPTALDH1A1KDM4EFGFR3LMNA | |
| SCHEMBL10036382 | 0.87 | WDR5 (0.43) | MAPTALDH1A1KDM4EFGFR3LMNA | |
| SCHEMBL10036381 | 0.87 | ALDH1A1 (0.43) | MAPTALDH1A1KDM4ELMNASMN1; SMN2 | |
| SCHEMBL27038673 | 0.86 | ALDH1A1 (0.43) | MAPTALDH1A1KDM4ELMNASMN1; SMN2 | |
| SCHEMBL10036127 | 0.85 | CHRNB2 (0.42) | MAPTALDH1A1KDM4EFGFR3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012053606-A1 | ARYLAMINOHETEROCYCLIC CARBOXAMIDE COMPOUND | アステラス製薬株式会社 (JP) | 2012-04-26 | — | — | WO | disclosed |