Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | SNCA | P37840 | 1/20 | 0.47 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3538406 | 0.86 | HSD17B10 (0.53) | HSD17B10MAPTHPGDRAB9ASMN1; SMN2 | |
| SCHEMBL4774235 | 0.84 | HSD17B10 (0.51) | HSD17B10MAPTHPGDRAB9ASMN1; SMN2 | |
| SCHEMBL1663340 | 0.84 | CYP19A1 (0.59) | HSD17B10MAPTHPGDRAB9ASMN1; SMN2 | |
| SCHEMBL14937641 | 0.83 | MAPT (0.51) | HSD17B10MAPTHPGDRAB9ASMN1; SMN2 | |
| SCHEMBL2910058 | 0.83 | MAPT (0.54) | HSD17B10MAPTHPGDRAB9ASMN1; SMN2 | |
| SCHEMBL10036380 | 0.83 | MAPT (0.58) | HSD17B10MAPTHPGDRAB9ASMN1; SMN2 | |
| SCHEMBL31534614 | 0.82 | RAB9A (0.55) | HSD17B10MAPTHPGDRAB9ASMN1; SMN2 | |
| SCHEMBL21331700 | 0.82 | MAPT (0.60) | HSD17B10MAPTHPGDRAB9ASMN1; SMN2 | |
| SCHEMBL526474 | 0.81 | TSHR (0.48) | MAPTHPGDRAB9ASMN1; SMN2LMNA | |
| SCHEMBL16943506 | 0.81 | ALDH1A1 (0.53) | MAPTHPGDRAB9ASMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012053606-A1 | ARYLAMINOHETEROCYCLIC CARBOXAMIDE COMPOUND | アステラス製薬株式会社 (JP) | 2012-04-26 | — | — | WO | disclosed |