Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 9/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | GFER | P55789 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | RAD52 | P43351 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29772135 | 0.89 | L3MBTL1 (0.42) | L3MBTL1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL15764136 | 0.88 | L3MBTL1 (0.53) | L3MBTL1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL29772091 | 0.88 | L3MBTL1 (0.41) | L3MBTL1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL29772099 | 0.86 | L3MBTL1 (0.41) | L3MBTL1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL29772064 | 0.86 | HTR4 (0.42) | L3MBTL1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL12309991 | 0.85 | L3MBTL1 (0.51) | L3MBTL1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL29772086 | 0.84 | HCRTR2 (0.41) | L3MBTL1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL28933806 | 0.84 | L3MBTL1 (0.71) | L3MBTL1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL12125970 | 0.83 | L3MBTL1 (0.49) | L3MBTL1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL13419681 | 0.83 | MAPT (0.54) | L3MBTL1MAPTALDH1A1LMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012053606-A1 | ARYLAMINOHETEROCYCLIC CARBOXAMIDE COMPOUND | アステラス製薬株式会社 (JP) | 2012-04-26 | — | — | WO | disclosed |