Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29772064 | 0.94 | HTR4 (0.42) | L3MBTL1MAPTGAAHTR4ACHE | |
| SCHEMBL29772099 | 0.91 | L3MBTL1 (0.41) | L3MBTL1MAPTGAAHTR4ACHE | |
| SCHEMBL29772135 | 0.90 | L3MBTL1 (0.42) | L3MBTL1MAPTGAAHTR4ACHE | |
| SCHEMBL10036404 | 0.88 | L3MBTL1 (0.51) | L3MBTL1MAPTGAAMEN1KMT2A | |
| SCHEMBL29772039 | 0.85 | ALDH1A1 (0.54) | MAPTGAAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL29772086 | 0.85 | HCRTR2 (0.41) | L3MBTL1MAPTGAAHTR4GSK3B | |
| SCHEMBL29772149 | 0.80 | ALDH1A1 (0.52) | MAPTGAAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL31334279 | 0.79 | CHRM4 (0.42) | MAPTGAAHTR4ACHEDRD2 | |
| SCHEMBL31712335 | 0.78 | DRD2 (0.54) | HTR1ADRD2HTR2ADRD3 | |
| SCHEMBL15764136 | 0.76 | L3MBTL1 (0.53) | L3MBTL1MAPTMEN1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114853846-A | Androgen receptor degradation agent and application thereof | 苏州国匡医药科技有限公司 | 2022-08-05 | — | — | CN | disclosed |