Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | TGFBR1 | P36897 | 9/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ATR | Q13535 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.38 |
| ▸ | ACVR1 | Q04771 | 2/20 | 0.38 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10036859 | 0.93 | FTO (0.43) | CYP1A2IDO1ALDH1A1KDM4EATR | |
| SCHEMBL10036858 | 0.80 | MAOA (0.44) | CYP1A2TGFBR1NPC1RAB9AALDH1A1 | |
| SCHEMBL10036864 | 0.76 | ALDH1A1 (0.45) | CYP1A2NPC1RAB9AALDH1A1MAPK1 | |
| SCHEMBL5480864 | 0.76 | CYP1A2 (0.58) | CYP1A2TGFBR1MAPK14NPC1RAB9A | |
| SCHEMBL23347077 | 0.75 | CYP1A2 (0.48) | CYP1A2IDO1TGFBR1MAPK14NPC1 | |
| SCHEMBL12269142 | 0.75 | CYP1A2 (0.48) | CYP1A2IDO1TGFBR1MAPK14NPC1 | |
| SCHEMBL14461196 | 0.75 | CYP1A2 (0.57) | CYP1A2IDO1TGFBR1MAPK14NPC1 | |
| SCHEMBL405626 | 0.75 | KDM4E (0.58) | CYP1A2IDO1TGFBR1NPC1RAB9A | |
| SCHEMBL10036863 | 0.74 | CNR1 (0.44) | CYP1A2ALDH1A1MAPK1HSD17B10KDM4E | |
| SCHEMBL10036866 | 0.74 | TNF (0.50) | CYP1A2ALDH1A1MAPK1HSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8101759-B2 | Acenaphthopyridine derivative, material of light-emitting element, light-emitting element, light-emitting device, and electronic appliance | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2012-01-24 | — | — | US | disclosed |
| US-8101759-B2 | Acenaphthopyridine derivative, material of light-emitting element, light-emitting element, light-emitting device, and electronic appliance | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2012-01-24 | — | — | US | disclosed |
| WO-2009119869-A1 | ACENAPHTHOPYRIDINE DERIVATIVE, MATERIAL OF LIGHT-EMITTING ELEMENT, LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, AND ELECTRONIC APPLIANCE | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2009-10-01 | — | — | WO | disclosed |
| US-20090247753-A1 | Acenaphthopyridine Derivative, Material of Light-Emitting Element, Light-Emitting Element, Light-Emitting Device, and Electronic Appliance | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. | 2009-10-01 | — | — | US | disclosed |
| US-20090247753-A1 | Acenaphthopyridine Derivative, Material of Light-Emitting Element, Light-Emitting Element, Light-Emitting Device, and Electronic Appliance | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. | 2009-10-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090247753-A1 | Acenaphthopyridine Derivative, Material of Light-Emitting Element, Light-Emitting Element, Light-Emitting Device, and Electronic Appliance | ACE, HRH2, ATP6AP1 | CYP1A2 27/4885IDO1 2663/4885TGFBR1 1712/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.