SCHEMBL1003737

SCHEMBL1003737

Brc1cccc(-c2cccc(Br)c2Br)c1Br

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.46
MAPK1 P28482 2/20 0.46
PIM1 P11309 1/20 0.38
CSNK1A1 P48729 1/20 0.38
CDK5 Q00535 1/20 0.38
ROCK1 Q13464 1/20 0.38
DYRK1A Q13627 1/20 0.38
LRRK2 Q5S007 1/20 0.38
CLK4 Q9HAZ1 1/20 0.38
DYRK1B Q9Y463 1/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
CA7 P43166 1/20 0.38
CA9 Q16790 1/20 0.38
PARP10 Q53GL7 1/20 0.35
PARP11 Q9NR21 1/20 0.35
GAA P10253 2/20 0.35
PBRM1 Q86U86 1/20 0.33
PDK2 Q15119 1/20 0.33
IDO1 P14902 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2802312 0.91 ALDH1A1 (0.52) ALDH1A1MAPK1PIM1CSNK1A1CDK5
SCHEMBL1259789 0.89 ALDH1A1 (0.39) ALDH1A1MAPK1PIM1CSNK1A1CDK5
SCHEMBL7523263 0.89 ALDH1A1 (0.50) ALDH1A1MAPK1PIM1CSNK1A1CDK5
Bicarbonate SCHEMBL11403105 0.87 ALDH1A1 (0.42) ALDH1A1MAPK1PIM1CSNK1A1CDK5
Ethylene SCHEMBL17363128 0.84 ALDH1A1 (0.36) ALDH1A1MAPK1PIM1CSNK1A1CDK5
SCHEMBL30231762 0.83 ALDH1A1 (0.39) ALDH1A1MAPK1PIM1CSNK1A1CDK5
SCHEMBL2804163 0.83 ALDH1A1 (0.39) ALDH1A1MAPK1PIM1CSNK1A1CDK5
SCHEMBL7519292 0.83 ALDH1A1 (0.62) ALDH1A1MAPK1CLK4MAPTHPGD
SCHEMBL7112111 0.83 ALDH1A1 (0.44) ALDH1A1MAPK1CA1CA2CA7
SCHEMBL7520229 0.83 ALDH1A1 (0.44) ALDH1A1MAPK1CA1CA2CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 643 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117180438-A Application of Nrf2 activator in preparation of medicine for relieving tetrabromodiphenyl ether-induced immune function injury 石河子大学 2023-12-08 CN claimed
US-20220135762-A1 METHOD FOR PREPARING FLAME RETARDANT AID AND FLAME RETARDANT RESIN COMPOSITION COMPRISING FLAME RETARDANT AID PREPARED BY SAME LG CHEMICAL LTD (KR) 2022-05-05 US claimed
CN-113803381-A Ultrahigh heat conduction powder metallurgy synchronizer cone ring and manufacturing method thereof 西安铝轻新材料科技有限公司 2021-12-17 CN claimed
EP-3907266-A1 METHOD FOR PRODUCING FLAME RETARDANT, AND FLAME RETARDANT RESIN COMPOSITION COMPRISING FLAME RETARDANT PRODUCED THEREBY LG Chem, Ltd. (KR) 2021-11-10 EP claimed
CN-109212072-B Polycyclic aromatic hydrocarbon soil gas source sink identification method 同济大学 2021-10-08 CN claimed
CN-113278260-A Composite modified epoxy resin, preparation method thereof and application thereof in automobile copper-clad plate 江苏扬农锦湖化工有限公司 2021-08-20 CN claimed
WO-2021060800-A1 METHOD FOR PRODUCING FLAME RETARDANT, AND FLAME RETARDANT RESIN COMPOSITION COMPRISING FLAME RETARDANT PRODUCED THEREBY 주식회사 엘지화학 2021-04-01 WO claimed
WO-2018148224-A1 PHOSPHOLIPID ETHER (PLE) CAR T CELL TUMOR TARGETING (CTCT) AGENTS Seattle Children's Hospital (dba Seattle Children's Research Institute) (US) 2018-08-16 WO claimed
WO-2012168261-A1 SOLID COMPOSITION COMPRISING A RADICAL FORMING COMPOUND AND A FLAME RETARDANT AKZO NOBEL CHEMICALS INTERNATIONAL B.V. (NL) 2012-12-13 WO claimed
EP-2510021-A1 PROCESS FOR THE POLYMERIZATION OF STYRENE Akzo Nobel Chemicals International B.V. (NL) 2012-10-17 EP claimed
US-20120245315-A1 PROCESS FOR THE POLYMERIZATION OF STYRENE AKZO NOBEL CHEMICALS INTERNATIONAL B.V. (NL) 2012-09-27 US claimed
US-8012891-B2 Flame resistant fabrics and process for making MILLIKEN & COMPANY (US) 2011-09-06 US claimed
US-8012890-B1 Flame resistant fabrics having a high synthetic content and process for making MILLIKEN & COMPANY (US) 2011-09-06 US claimed
WO-2011069983-A1 PROCESS FOR THE POLYMERIZATION OF STYRENE AKZO NOBEL CHEMICALS INTERNATIONAL B.V. (NL) 2011-06-16 WO claimed
US-20100210162-A1 FLAME RESISTANT FABRICS AND PROCESS FOR MAKING LI SHULONG 2010-08-19 US claimed
US-7713891-B1 Flame resistant fabrics and process for making MILLIKEN & COMPANY (US) 2010-05-11 US claimed
WO-2008020979-A2 FLAME-RETARDANT TREATMENTS FOR CELLULOSE-CONTAINING FABRICS AND THE FABRICS SO TREATED MILLIKEN & COMPANY (US) 2008-02-21 WO claimed
US-20080038973-A1 Flame-retardant treatments for cellulose-containing fabrics and the fabrics so treated SASSER KIMILA C 2008-02-14 US claimed
EP-0558997-B1 Process for reducing the halogen-content of polyhalogenated aromatics BAYER AG (DE) 1995-11-22 EP claimed
US-5292975-A Platinum metal catalyst BAYER AKTIENGESELLSCHAFT (DE) 1994-03-08 US claimed