SCHEMBL7523263

SCHEMBL7523263

Brc1ccccc1-c1ccccc1-c1cccc(Br)c1Br

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.50
MAPK1 P28482 4/20 0.50
PBRM1 Q86U86 1/20 0.38
IDO1 P14902 1/20 0.38
LMNA P02545 1/20 0.38
MAPT P10636 3/20 0.36
HSD17B10 Q99714 2/20 0.36
MAOA P21397 2/20 0.36
MAOB P27338 2/20 0.36
GAA P10253 2/20 0.36
HPGD P15428 2/20 0.36
DCUN1D1 Q96GG9 2/20 0.36
KDM4E B2RXH2 1/20 0.36
MPI P34949 1/20 0.36
APOBEC3G Q9HC16 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
HKDC1 Q2TB90 1/20 0.36
TSHR P16473 2/20 0.36
L3MBTL1 Q9Y468 2/20 0.36
ATM Q13315 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2802312 0.97 ALDH1A1 (0.52) ALDH1A1MAPK1PBRM1IDO1LMNA
SCHEMBL1003737 0.89 ALDH1A1 (0.46) ALDH1A1MAPK1PBRM1IDO1LMNA
SCHEMBL7519287 0.86 ALDH1A1 (0.63) ALDH1A1MAPK1PBRM1IDO1LMNA
SCHEMBL31465796 0.86 ALDH1A1 (0.63) ALDH1A1MAPK1PBRM1IDO1LMNA
SCHEMBL16193393 0.83 ALDH1A1 (0.55) ALDH1A1MAPK1PBRM1IDO1LMNA
SCHEMBL7519292 0.83 ALDH1A1 (0.62) ALDH1A1MAPK1MAPTHSD17B10HPGD
SCHEMBL7520229 0.83 ALDH1A1 (0.44) ALDH1A1MAPK1PBRM1IDO1LMNA
SCHEMBL31295703 0.83 ALDH1A1 (0.67) ALDH1A1MAPK1PBRM1IDO1LMNA
SCHEMBL358976 0.83 ALDH1A1 (0.67) ALDH1A1MAPK1PBRM1IDO1LMNA
Ether SCHEMBL2802892 0.81 ALDH1A1 (0.39) ALDH1A1MAPK1PBRM1IDO1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0889920-B1 POLYPHENYLENE OLIGOMERS AND POLYMERS DOW CHEMICAL CO (US) 2002-02-13 EP disclosed
US-6288188-B1 ACETYLENIC POLYMERS; INTEGRATED CIRCUITS, DIELECTRICS, MICROELECTRONICS THE DOW CHEMICAL COMPANY 2001-09-11 US disclosed
US-5965679-A BASED A BISCYCLOPENTADIENONE AND AN AROMATIC DIACETYLENE; CURING; LOW DIELECTRIC; INTEGRATED CIRCUITS; MICROELECTRONICS; PRINTED CIRCUITS THE DOW CHEMICAL COMPANY (US) 1999-10-12 US disclosed
EP-0889920-A1 POLYPHENYLENE OLIGOMERS AND POLYMERS THE DOW CHEMICAL COMPANY (US) 1999-01-13 EP disclosed
WO-1998011149-A1 POLYPHENYLENE OLIGOMERS AND POLYMERS THE DOW CHEMICAL COMPANY (US) 1998-03-19 WO disclosed