SCHEMBL7520229

SCHEMBL7520229

Brc1ccccc1-c1c(Br)cccc1-c1cccc(Br)c1Br

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.44
MAPK1 P28482 3/20 0.44
MAPT P10636 5/20 0.38
L3MBTL1 Q9Y468 2/20 0.38
MEN1 O00255 1/20 0.38
POLB P06746 1/20 0.38
HTT P42858 1/20 0.38
KMT2A Q03164 1/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
CA7 P43166 1/20 0.38
CA9 Q16790 1/20 0.38
PDK2 Q15119 1/20 0.38
HSD17B10 Q99714 1/20 0.37
PBRM1 Q86U86 1/20 0.34
IDO1 P14902 1/20 0.34
LMNA P02545 1/20 0.34
MAOA P21397 2/20 0.33
MAOB P27338 2/20 0.33
HPGD P15428 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2802312 0.85 ALDH1A1 (0.52) ALDH1A1MAPK1MAPTL3MBTL1CA1
SCHEMBL7523263 0.83 ALDH1A1 (0.50) ALDH1A1MAPK1MAPTL3MBTL1PDK2
SCHEMBL1768545 0.83 ALDH1A1 (0.55) ALDH1A1MAPK1MAPTL3MBTL1MEN1
SCHEMBL29803148 0.83 ALDH1A1 (0.55) ALDH1A1MAPK1MAPTL3MBTL1MEN1
SCHEMBL1003737 0.83 ALDH1A1 (0.46) ALDH1A1MAPK1MAPTCA1CA2
SCHEMBL31275971 0.80 ALDH1A1 (0.52) ALDH1A1MAPK1MAPTL3MBTL1MEN1
SCHEMBL7606252 0.80 ALDH1A1 (0.46) ALDH1A1MAPK1MAPTL3MBTL1MEN1
SCHEMBL19237177 0.80 ALDH1A1 (0.46) ALDH1A1MAPK1MAPTL3MBTL1MEN1
SCHEMBL1768510 0.77 ALDH1A1 (0.70) ALDH1A1MAPK1MAPTL3MBTL1MEN1
SCHEMBL1768195 0.77 ALDH1A1 (0.52) ALDH1A1MAPK1MAPTL3MBTL1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0889920-B1 POLYPHENYLENE OLIGOMERS AND POLYMERS DOW CHEMICAL CO (US) 2002-02-13 EP disclosed
US-6288188-B1 ACETYLENIC POLYMERS; INTEGRATED CIRCUITS, DIELECTRICS, MICROELECTRONICS THE DOW CHEMICAL COMPANY 2001-09-11 US disclosed
US-5965679-A BASED A BISCYCLOPENTADIENONE AND AN AROMATIC DIACETYLENE; CURING; LOW DIELECTRIC; INTEGRATED CIRCUITS; MICROELECTRONICS; PRINTED CIRCUITS THE DOW CHEMICAL COMPANY (US) 1999-10-12 US disclosed
EP-0889920-A1 POLYPHENYLENE OLIGOMERS AND POLYMERS THE DOW CHEMICAL COMPANY (US) 1999-01-13 EP disclosed
WO-1998011149-A1 POLYPHENYLENE OLIGOMERS AND POLYMERS THE DOW CHEMICAL COMPANY (US) 1998-03-19 WO disclosed