Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 9/20 | 0.43 |
| ▸ | TOP2A | P11388 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | CACNA1G | O43497 | 5/20 | 0.38 |
| ▸ | CACNA1H | O95180 | 5/20 | 0.38 |
| ▸ | CACNA1I | Q9P0X4 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3980956 | 0.91 | HTR3A (0.43) | HTR3ACYP2C19KCNH2CACNA1GCACNA1H | |
| SCHEMBL1005833 | 0.91 | HTR3A (0.43) | HTR3ACYP2C19KCNH2CACNA1GCACNA1H | |
| SCHEMBL3981692 | 0.90 | HTR3A (0.43) | HTR3ACYP2C19KCNH2CACNA1GCACNA1H | |
| SCHEMBL1004932 | 0.90 | HTR3A (0.43) | HTR3ACYP2C19KCNH2CACNA1GCACNA1H | |
| Lithium Ion SCHEMBL1004930 | 0.89 | HTR3A (0.42) | HTR3ACYP2C19KCNH2CACNA1GCACNA1H | |
| SCHEMBL1006101 | 0.86 | HTR3A (0.50) | HTR3ATOP2ACYP2C19KCNH2MEN1 | |
| SCHEMBL1006252 | 0.84 | HTR3A (0.47) | HTR3ATOP2ACYP2C19KCNH2 | |
| SCHEMBL1005782 | 0.83 | HTR3A (0.47) | HTR3ACYP2C19KCNH2 | |
| SCHEMBL1005784 | 0.83 | HTR3A (0.68) | HTR3AKCNH2 | |
| SCHEMBL1005786 | 0.83 | HTR3A (0.68) | HTR3AKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7863271-B2 | 2-aminobenzoxazole carboxamides as 5HT3 modulators | ALBANY MOLECULAR RESEARCH, INC. (US) | 2011-01-04 | — | — | US | disclosed |
| US-20080255114-A1 | 2-AMINOBENZOXAZOLE CARBOXAMIDES AS 5HT3 MODULATORS | AMR TECHNOLOGY, INC. (US) | 2008-10-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080255114-A1 | 2-AMINOBENZOXAZOLE CARBOXAMIDES AS 5HT3 MODULATORS | HTR3E, HTR3C, HTR3A | HTR3A 3/4885TOP2A 323/4885CYP2C19 169/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.