SCHEMBL10037554

SCHEMBL10037554

CC1=CC(=O)N(C(C)C(=O)NC(C)N)C1=O

nearest known ligand 0.38

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
POLB P06746 3/20 0.37
ALDH1A1 P00352 3/20 0.35
LMNA P02545 1/20 0.35
HTT P42858 1/20 0.35
HPGD P15428 1/20 0.33
MAPT P10636 1/20 0.31
KDM4E B2RXH2 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10037551 0.78 POLB (0.38) POLBALDH1A1LMNAHTTHPGD
SCHEMBL10037553 0.78 SLC1A2 (0.38) ALDH1A1LMNAHTTHPGDKDM4E
SCHEMBL9064507 0.76 CSNK2A2 (0.46) POLBALDH1A1LMNAHTTHPGD
SCHEMBL10050025 0.70 ALDH1A1 (0.33) POLBALDH1A1LMNAHTTKDM4E
SCHEMBL4404816 0.69 XPO1 (0.33)
SCHEMBL15394245 0.68 JUN (0.33) ALDH1A1LMNAMAPT
SCHEMBL14868141 0.68 JUN (0.33) ALDH1A1LMNAMAPT
SCHEMBL10037952 0.68 POLB (0.33) POLBMAPT
SCHEMBL16266924 0.67 MEN1 (0.38) POLBALDH1A1LMNAHPGDMAPT
SCHEMBL8440537 0.67 MEN1 (0.38) POLBALDH1A1LMNAHPGDMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8124791-B2 Active energy ray curable liquid composition and liquid cartridge CANON KABUSHIKI KAISHA (JP) 2012-02-28 US disclosed
US-20100094024-A1 ACTIVE ENERGY RAY CURABLE LIQUID COMPOSITION AND LIQUID CARTRIDGE CANON KABUSHIKI KAISHA (JP) 2010-04-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100094024-A1 ACTIVE ENERGY RAY CURABLE LIQUID COMPOSITION AND LIQUID CARTRIDGE C9, MLX, CHRM1 POLB 207/4885ALDH1A1 3555/4885LMNA 99/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.