Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10038470 | 0.86 | HPGD (0.36) | RAB9AMGLLALDH1A1MAPTLMNA | |
| SCHEMBL10038476 | 0.82 | MGLL (0.53) | KMT2AGRM5MGLLALDH1A1MEN1 | |
| SCHEMBL21756621 | 0.76 | MGLL (0.46) | KMT2ARAB9AGRM5MGLLALDH1A1 | |
| SCHEMBL10038477 | 0.76 | KMT2A (0.43) | KMT2ARAB9AGRM5ALDH1A1MEN1 | |
| SCHEMBL96043 | 0.75 | MGLL (0.52) | KMT2ARAB9AMGLLALDH1A1MEN1 | |
| SCHEMBL28527836 | 0.73 | MGLL (0.45) | KMT2AGRM5MGLLALDH1A1MEN1 | |
| SCHEMBL419321 | 0.73 | MAPK1 (0.44) | KMT2ARAB9ATDP1ALDH1A1MEN1 | |
| SCHEMBL15282329 | 0.72 | MAPK1 (0.43) | KMT2ARAB9ATDP1ALDH1A1MEN1 | |
| SCHEMBL13133148 | 0.71 | HSD17B10 (0.54) | KMT2ATDP1MGLLALDH1A1MEN1 | |
| SCHEMBL3426128 | 0.70 | MAPK1 (0.43) | KMT2ARAB9ATDP1ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8158748-B2 | Hetero-functional compounds and methods for use thereof | DESIGNER MOLECULES, INC. (US) | 2012-04-17 | — | — | US | disclosed |
| US-8158748-B2 | Hetero-functional compounds and methods for use thereof | DESIGNER MOLECULES, INC. (US) | 2012-04-17 | — | — | US | disclosed |
| US-20100041845-A1 | HETERO-FUNCTIONAL COMPOUNDS AND METHODS FOR USE THEREOF | DESIGNER MOLECULES, INC. (US) | 2010-02-18 | — | — | US | disclosed |
| US-20100041845-A1 | HETERO-FUNCTIONAL COMPOUNDS AND METHODS FOR USE THEREOF | DESIGNER MOLECULES, INC. (US) | 2010-02-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100041845-A1 | HETERO-FUNCTIONAL COMPOUNDS AND METHODS FOR USE THEREOF | C9, C3AR1, C1S | KMT2A 3084/4885RAB9A 4142/4885TDP1 3679/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.