Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.34 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10038465 | 0.86 | KMT2A (0.39) | MAPTL3MBTL1LMNAALDH1A1RAB9A | |
| SCHEMBL10038471 | 0.80 | MGLL (0.49) | HPGDNPSR1LMNAALDH1A1CACNA1B | |
| SCHEMBL4391609 | 0.75 | MGLL (0.49) | HPGDKDM4EPOLBLMNAALDH1A1 | |
| SCHEMBL94147 | 0.74 | MGLL (0.46) | NPSR1RAB9AMGLL | |
| SCHEMBL10038464 | 0.74 | POLB (0.46) | HPGDKDM4EMAPTL3MBTL1POLB | |
| SCHEMBL28434246 | 0.74 | MGLL (0.59) | KDM4EMAPTPOLBLMNAALDH1A1 | |
| SCHEMBL15347091 | 0.73 | RAB9A (0.55) | MAPTL3MBTL1POLBLMNARAB9A | |
| SCHEMBL419937 | 0.72 | THRB (0.41) | KDM4EMAPTL3MBTL1ALDH1A1HTT | |
| SCHEMBL8468148 | 0.72 | LMNA (0.49) | HPGDKDM4EMAPTL3MBTL1POLB | |
| SCHEMBL720020 | 0.71 | DRD2 (0.48) | HPGDNPSR1KDM4EL3MBTL1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8158748-B2 | Hetero-functional compounds and methods for use thereof | DESIGNER MOLECULES, INC. (US) | 2012-04-17 | — | — | US | disclosed |
| US-8158748-B2 | Hetero-functional compounds and methods for use thereof | DESIGNER MOLECULES, INC. (US) | 2012-04-17 | — | — | US | disclosed |
| US-20100041845-A1 | HETERO-FUNCTIONAL COMPOUNDS AND METHODS FOR USE THEREOF | DESIGNER MOLECULES, INC. (US) | 2010-02-18 | — | — | US | disclosed |
| US-20100041845-A1 | HETERO-FUNCTIONAL COMPOUNDS AND METHODS FOR USE THEREOF | DESIGNER MOLECULES, INC. (US) | 2010-02-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100041845-A1 | HETERO-FUNCTIONAL COMPOUNDS AND METHODS FOR USE THEREOF | C9, C3AR1, C1S | HPGD 1999/4885NPSR1 560/4885KDM4E 3373/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.